Rufinamide (RUF) suppresses inflammation and maintains the integrity of the blood–brain barrier during kainic acid-induced brain damage
Rufinamide (RUF) is a structurally unique anti-epileptic drug, but its protective mechanism against brain injury remains unclear. In the present study, we validated how the RUF protected mice with kainic acid (KA)-induced neuronal damage. To achieve that, a mouse epilepsy model was established by KA...
Guardado en:
Autores principales: | Yu Huaxu, He Bin, Han Xu, Yan Ting |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
De Gruyter
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/6d0d23485c104afd97f40409ac49d0b5 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Evidence of Neuroinflammation and Blood–Brain Barrier Disruption in Women with Preeclampsia and Eclampsia
por: Lina Bergman, et al.
Publicado: (2021) -
Optimization of Hypoxic Brain Injuries Diagnostics in Full-Term Newborns
por: M. S. Panova, et al.
Publicado: (2021) -
Hippocampal Function Is Impaired by a Short-Term High-Fat Diet in Mice: Increased Blood–Brain Barrier Permeability and Neuroinflammation as Triggering Events
por: Gabriela Cristina de Paula, et al.
Publicado: (2021) -
Traumatic Brain Injury and Neuroinflammation: Review of the Main Biomarkers
por: A. I. Zudova, et al.
Publicado: (2020) -
Overcoming the Blood–Brain Barrier: Successes and Challenges in Developing Nanoparticle-Mediated Drug Delivery Systems for the Treatment of Brain Tumours
por: Ferraris C, et al.
Publicado: (2020)