Competition between microtubule-associated proteins directs motor transport
Motor and non-motor microtubule-associated proteins (MAPs) bind to the microtubule lattice, but it is unclear how their binding activities are coordinated and how this impacts motor transport. Here the authors show how MAP competition controls microtubule access to determine the distribution and bal...
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Nature Portfolio
2018
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oai:doaj.org-article:6d1800048a2e42c8acaa0aa6015b3b0c2021-12-02T15:33:43ZCompetition between microtubule-associated proteins directs motor transport10.1038/s41467-018-03909-22041-1723https://doaj.org/article/6d1800048a2e42c8acaa0aa6015b3b0c2018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03909-2https://doaj.org/toc/2041-1723Motor and non-motor microtubule-associated proteins (MAPs) bind to the microtubule lattice, but it is unclear how their binding activities are coordinated and how this impacts motor transport. Here the authors show how MAP competition controls microtubule access to determine the distribution and balance of motor activity.Brigette Y. MonroyDanielle L. SawyerBryce E. AckermannMelissa M. BordenTracy C. TanKassandra M. Ori-McKenneyNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018) |
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Science Q |
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Science Q Brigette Y. Monroy Danielle L. Sawyer Bryce E. Ackermann Melissa M. Borden Tracy C. Tan Kassandra M. Ori-McKenney Competition between microtubule-associated proteins directs motor transport |
description |
Motor and non-motor microtubule-associated proteins (MAPs) bind to the microtubule lattice, but it is unclear how their binding activities are coordinated and how this impacts motor transport. Here the authors show how MAP competition controls microtubule access to determine the distribution and balance of motor activity. |
format |
article |
author |
Brigette Y. Monroy Danielle L. Sawyer Bryce E. Ackermann Melissa M. Borden Tracy C. Tan Kassandra M. Ori-McKenney |
author_facet |
Brigette Y. Monroy Danielle L. Sawyer Bryce E. Ackermann Melissa M. Borden Tracy C. Tan Kassandra M. Ori-McKenney |
author_sort |
Brigette Y. Monroy |
title |
Competition between microtubule-associated proteins directs motor transport |
title_short |
Competition between microtubule-associated proteins directs motor transport |
title_full |
Competition between microtubule-associated proteins directs motor transport |
title_fullStr |
Competition between microtubule-associated proteins directs motor transport |
title_full_unstemmed |
Competition between microtubule-associated proteins directs motor transport |
title_sort |
competition between microtubule-associated proteins directs motor transport |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/6d1800048a2e42c8acaa0aa6015b3b0c |
work_keys_str_mv |
AT brigetteymonroy competitionbetweenmicrotubuleassociatedproteinsdirectsmotortransport AT daniellelsawyer competitionbetweenmicrotubuleassociatedproteinsdirectsmotortransport AT bryceeackermann competitionbetweenmicrotubuleassociatedproteinsdirectsmotortransport AT melissamborden competitionbetweenmicrotubuleassociatedproteinsdirectsmotortransport AT tracyctan competitionbetweenmicrotubuleassociatedproteinsdirectsmotortransport AT kassandramorimckenney competitionbetweenmicrotubuleassociatedproteinsdirectsmotortransport |
_version_ |
1718387029414248448 |