Microtubule-dependent balanced cell contraction and luminal-matrix modification accelerate epithelial tube fusion

During tracheal tube fusion in Drosophila, a pair of tip cells form an adherens junction and then fuse their plasma membranes. Here the authors show that a balanced pulling force mediated by myosin and microtubules, as well as localized deposition of matrix, promotes plasma membrane fusion.

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Autores principales: Kagayaki Kato, Bo Dong, Housei Wada, Miho Tanaka-Matakatsu, Yoshimasa Yagi, Shigeo Hayashi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/6d24a2bc0cc747e38d1fb850bb401799
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