Current and emerging biomarkers of frailty in the elderly

Ahmed Al Saedi,1,2 Jack Feehan,1,2 Steven Phu,1,2 Gustavo Duque1,2 1Australian Institute for Musculoskeletal Science (AIMSS), University of Melbourne and Western Health, St Albans, Melbourne, VIC, Australia; 2Department of Medicine, Western Health, Melbourne Medical School, University of Melbourne,...

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Autores principales:	Al Saedi A, Feehan J, Phu S, Duque G
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2019
Materias:	Frailty biomarkers COP cells mesenchymal stem cells disability elderly. Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/6d26ee57585744c5ba742233a134a637
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spelling	oai:doaj.org-article:6d26ee57585744c5ba742233a134a6372021-12-02T05:37:35ZCurrent and emerging biomarkers of frailty in the elderly1178-1998https://doaj.org/article/6d26ee57585744c5ba742233a134a6372019-02-01T00:00:00Zhttps://www.dovepress.com/current-and-emerging-biomarkers-of-frailty-in-the-elderly-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Ahmed Al Saedi,1,2 Jack Feehan,1,2 Steven Phu,1,2 Gustavo Duque1,2 1Australian Institute for Musculoskeletal Science (AIMSS), University of Melbourne and Western Health, St Albans, Melbourne, VIC, Australia; 2Department of Medicine, Western Health, Melbourne Medical School, University of Melbourne, St Albans, Melbourne, VIC, Australia Abstract: The term “frailty” is used to describe a subset of older adults who appear weaker and more vulnerable than their age-matched counterparts, despite having similar comorbidities, demography, sex, and age. The diagnosis of frailty is usually clinical and based on specific criteria, which are sometimes inconsistent. Therefore, there is an increasing need to identify and validate robust biomarkers for this condition. In this review, we summarize current evidence on the validity and practicality of the most commonly used biomarkers for frailty, while also comparing them with new upcoming strategies to identify this condition. Keywords: frailty, biomarkers, COP cells, mesenchymal stem cells, disability, elderlyAl Saedi AFeehan JPhu SDuque GDove Medical PressarticleFrailtybiomarkersCOP cellsmesenchymal stem cellsdisabilityelderly.GeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 14, Pp 389-398 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Frailty biomarkers COP cells mesenchymal stem cells disability elderly. Geriatrics RC952-954.6
spellingShingle	Frailty biomarkers COP cells mesenchymal stem cells disability elderly. Geriatrics RC952-954.6 Al Saedi A Feehan J Phu S Duque G Current and emerging biomarkers of frailty in the elderly
description	Ahmed Al Saedi,1,2 Jack Feehan,1,2 Steven Phu,1,2 Gustavo Duque1,2 1Australian Institute for Musculoskeletal Science (AIMSS), University of Melbourne and Western Health, St Albans, Melbourne, VIC, Australia; 2Department of Medicine, Western Health, Melbourne Medical School, University of Melbourne, St Albans, Melbourne, VIC, Australia Abstract: The term “frailty” is used to describe a subset of older adults who appear weaker and more vulnerable than their age-matched counterparts, despite having similar comorbidities, demography, sex, and age. The diagnosis of frailty is usually clinical and based on specific criteria, which are sometimes inconsistent. Therefore, there is an increasing need to identify and validate robust biomarkers for this condition. In this review, we summarize current evidence on the validity and practicality of the most commonly used biomarkers for frailty, while also comparing them with new upcoming strategies to identify this condition. Keywords: frailty, biomarkers, COP cells, mesenchymal stem cells, disability, elderly
format	article
author	Al Saedi A Feehan J Phu S Duque G
author_facet	Al Saedi A Feehan J Phu S Duque G
author_sort	Al Saedi A
title	Current and emerging biomarkers of frailty in the elderly
title_short	Current and emerging biomarkers of frailty in the elderly
title_full	Current and emerging biomarkers of frailty in the elderly
title_fullStr	Current and emerging biomarkers of frailty in the elderly
title_full_unstemmed	Current and emerging biomarkers of frailty in the elderly
title_sort	current and emerging biomarkers of frailty in the elderly
publisher	Dove Medical Press
publishDate	2019
url	https://doaj.org/article/6d26ee57585744c5ba742233a134a637
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_version_	1718400302260944896

Current and emerging biomarkers of frailty in the elderly

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