Acetaldehyde exposure underlies functional defects in monocytes induced by excessive alcohol consumption

Acetaldehyde exposure underlies functional defects in monocytes induced by excessive alcohol consumption

Abstract Increased intestinal permeability and hepatic macrophage activation by endotoxins are involved in alcohol-induced liver injury pathogenesis. Long-term alcohol exposure conversely induces endotoxin immune tolerance; however, the precise mechanism and reversibility are unclear. Seventy-two al...

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Main Authors: Shunsuke Shiba, Nobuhiro Nakamoto, Po-Sung Chu, Keisuke Ojiro, Nobuhito Taniki, Akihiro Yamaguchi, Rei Morikawa, Tadashi Katayama, Aya Yoshida, Ryo Aoki, Toshiaki Teratani, Takahiro Suzuki, Takeshi Miyamoto, Sachiko Hara, Akira Yokoyama, Takanori Kanai
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/6d33fb9776d94b5a89dadc3ad3ff5ad0
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https://doaj.org/article/6d33fb9776d94b5a89dadc3ad3ff5ad0

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