LYMPHOCYTE-TO PLATELET ADHERENCE IN PATIENTS WITH ERYSIPELAS

We observed twenty patients (12 women and 8 men) with erythematous-bullous erysipelas of moderate grade, and twenty patients (10 men and 10 women) with erythematous form of the disease, 45 to 55 years old. All the patients were diagnosed with primary inflammatory disease located at the lower extremi...

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Autores principales:	A. N. Emelyanova, Yu. A. Vitkovskiy
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	erysipelas lymphocyte-to-platelet adherence immunity haemostasis Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/6d347658ce7a4034b15f0898bf2ad0b5
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spelling	oai:doaj.org-article:6d347658ce7a4034b15f0898bf2ad0b52021-11-18T08:03:38ZLYMPHOCYTE-TO PLATELET ADHERENCE IN PATIENTS WITH ERYSIPELAS1563-06252313-741X10.15789/1563-0625-2013-2-163-168https://doaj.org/article/6d347658ce7a4034b15f0898bf2ad0b52014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/107https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XWe observed twenty patients (12 women and 8 men) with erythematous-bullous erysipelas of moderate grade, and twenty patients (10 men and 10 women) with erythematous form of the disease, 45 to 55 years old. All the patients were diagnosed with primary inflammatory disease located at the lower extremities. The patients were admitted to the hospital within 1 or 3 days from the onset of clinical signs of the disease. In all patients, laboratory studies were performed at 3 and 12 days after clinical onset of the disease. Control group consisted of 55 age- and sex-matched healthy persons. All the patients received standard therapy, including antibiotics, desensitization and detoxifying drugs. Indices of l;ymphocyte-to-platelet adhesion (LPA) were determined in patients with different forms of erysipelas,. It has been found that LPA parameters were sharply decreased since the beginning of the disease, in spite of near-normal absolute lymphocyte counts, as compared with healthy controls at these terms. A simultaneous reduction in adherence was registered. At day 12, the LPA parameters were increased in the patients, with absence of significant changes in absolute lymphocyte contents against control values, the adhesion rates proved to be increased as well. Hence, a reduced ability of blood lymphocytes to adhere to the surface of platelets was revealed in erysipelas. Dynamics of LPA parameters may serve as an indicator of treatment efficiency.A. N. EmelyanovaYu. A. VitkovskiySPb RAACIarticleerysipelaslymphocyte-to-platelet adherenceimmunityhaemostasisImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 15, Iss 2, Pp 163-168 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	erysipelas lymphocyte-to-platelet adherence immunity haemostasis Immunologic diseases. Allergy RC581-607
spellingShingle	erysipelas lymphocyte-to-platelet adherence immunity haemostasis Immunologic diseases. Allergy RC581-607 A. N. Emelyanova Yu. A. Vitkovskiy LYMPHOCYTE-TO PLATELET ADHERENCE IN PATIENTS WITH ERYSIPELAS
description	We observed twenty patients (12 women and 8 men) with erythematous-bullous erysipelas of moderate grade, and twenty patients (10 men and 10 women) with erythematous form of the disease, 45 to 55 years old. All the patients were diagnosed with primary inflammatory disease located at the lower extremities. The patients were admitted to the hospital within 1 or 3 days from the onset of clinical signs of the disease. In all patients, laboratory studies were performed at 3 and 12 days after clinical onset of the disease. Control group consisted of 55 age- and sex-matched healthy persons. All the patients received standard therapy, including antibiotics, desensitization and detoxifying drugs. Indices of l;ymphocyte-to-platelet adhesion (LPA) were determined in patients with different forms of erysipelas,. It has been found that LPA parameters were sharply decreased since the beginning of the disease, in spite of near-normal absolute lymphocyte counts, as compared with healthy controls at these terms. A simultaneous reduction in adherence was registered. At day 12, the LPA parameters were increased in the patients, with absence of significant changes in absolute lymphocyte contents against control values, the adhesion rates proved to be increased as well. Hence, a reduced ability of blood lymphocytes to adhere to the surface of platelets was revealed in erysipelas. Dynamics of LPA parameters may serve as an indicator of treatment efficiency.
format	article
author	A. N. Emelyanova Yu. A. Vitkovskiy
author_facet	A. N. Emelyanova Yu. A. Vitkovskiy
author_sort	A. N. Emelyanova
title	LYMPHOCYTE-TO PLATELET ADHERENCE IN PATIENTS WITH ERYSIPELAS
title_short	LYMPHOCYTE-TO PLATELET ADHERENCE IN PATIENTS WITH ERYSIPELAS
title_full	LYMPHOCYTE-TO PLATELET ADHERENCE IN PATIENTS WITH ERYSIPELAS
title_fullStr	LYMPHOCYTE-TO PLATELET ADHERENCE IN PATIENTS WITH ERYSIPELAS
title_full_unstemmed	LYMPHOCYTE-TO PLATELET ADHERENCE IN PATIENTS WITH ERYSIPELAS
title_sort	lymphocyte-to platelet adherence in patients with erysipelas
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/6d347658ce7a4034b15f0898bf2ad0b5
work_keys_str_mv	AT anemelyanova lymphocytetoplateletadherenceinpatientswitherysipelas AT yuavitkovskiy lymphocytetoplateletadherenceinpatientswitherysipelas
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LYMPHOCYTE-TO PLATELET ADHERENCE IN PATIENTS WITH ERYSIPELAS

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