A Bayesian approach to extracting free-energy profiles from cryo-electron microscopy experiments

A Bayesian approach to extracting free-energy profiles from cryo-electron microscopy experiments

Abstract Cryo-electron microscopy (cryo-EM) extracts single-particle density projections of individual biomolecules. Although cryo-EM is widely used for 3D reconstruction, due to its single-particle nature it has the potential to provide information about a biomolecule’s conformational variability a...

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Autores principales: Julian Giraldo-Barreto, Sebastian Ortiz, Erik H. Thiede, Karen Palacio-Rodriguez, Bob Carpenter, Alex H. Barnett, Pilar Cossio
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/6d37047f25404889a06af55c9b39dae6
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