Modular synthesis of chiral 1,2-dihydropyridines via Mannich/Wittig/cycloisomerization sequence that internally reuses waste

1,2-Dihydropyridines are valuable precursors for the synthesis of biologically relevant piperidines and pyridines, but the methods for their synthesis are underdeveloped. Here, the authors report a modular organocatalytic Mannich/Wittig/cycloisomerization sequence to access chiral 1,2-dihydropyridin...

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Bibliographic Details
Main Authors: Bo-Shuai Mu, Xiao-Yuan Cui, Xing-Ping Zeng, Jin-Sheng Yu, Jian Zhou
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/6d370ec84c8a4ecea03e8d81ab8c388e
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