Systematic Synergy of Glucose and GLP-1 to Stimulate Insulin Secretion Revealed by Quantitative Phosphoproteomics

Abstract GLP-1 synergizes with glucose in regulating pancreatic β-cell function, including facilitating β-cell survival and insulin secretion. Though it has been widely accepted that phosphorylation is extremely important in regulating β-cell functions, our knowledge to the global mechanism is still...

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Auteurs principaux: Jia-shu Tang, Qing-run Li, Jia-ming Li, Jia-rui Wu, Rong Zeng
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/6d3926a792894f9e88ffe8e68d2075cf
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