Prevalence of Signs and Symptoms of Dry Eye Disease 5 to 15 After Refractive Surgery

Prevalence of Signs and Symptoms of Dry Eye Disease 5 to 15 After Refractive Surgery

Bjørn Gjerdrum,1,2 Kjell Gunnar Gundersen,2 Per Olof Lundmark,1 Rick Potvin,3 Bente Monica Aakre1 1Department of Optometry, Radiography and Lighting Design, University of South-Eastern Norway, Kongsberg, Norway; 2Ifocus Eye Clinic, Haugesund, Norway; 3Science in Vision, Akron, NY, USACorr...

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Autores principales: Gjerdrum B, Gundersen KG, Lundmark PO, Potvin R, Aakre BM
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2020
Materias:
tear film
hyperosmolarity
osdi
post lvc
Ophthalmology
RE1-994
Acceso en línea:https://doaj.org/article/6d39af6310a24fcbb945fc2747447ae8
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spelling oai:doaj.org-article:6d39af6310a24fcbb945fc2747447ae82021-12-02T09:12:24ZPrevalence of Signs and Symptoms of Dry Eye Disease 5 to 15 After Refractive Surgery1177-5483https://doaj.org/article/6d39af6310a24fcbb945fc2747447ae82020-01-01T00:00:00Zhttps://www.dovepress.com/prevalence-of-signs-and-symptoms-of-dry-eye-disease-5-to-15-after-refr-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Bjørn Gjerdrum,1,2 Kjell Gunnar Gundersen,2 Per Olof Lundmark,1 Rick Potvin,3 Bente Monica Aakre1 1Department of Optometry, Radiography and Lighting Design, University of South-Eastern Norway, Kongsberg, Norway; 2Ifocus Eye Clinic, Haugesund, Norway; 3Science in Vision, Akron, NY, USACorrespondence: Bjørn Gjerdrum Brønngata 36, Stavanger 4008, NorwayTel +47 415 11 935Email bjorn@ifocus.noPurpose: To compare the prevalence of dry eye disease (DED) as determined by signs and symptoms in patients with a history of laser vision correction (LVC) or implantable collamer lens (ICL) implantation 5– 15 years ago with a matched control group with no history of refractive surgery.Patient and Methods: This was a cross-sectional case-control study. The subject population included patients who had LVC or ICL 5 to 15 years ago. The control group was age matched. A test eye was randomly chosen. Subjects were required to have good ocular health. DED was evaluated using categorical cut-off criteria for tear film osmolarity (measured in both eyes), the subjective Ocular Surface Disease Index (OSDI), the dynamic Objective Scatter Index (OSI), non-invasive keratography tear break-up time (NIKBUT), meibography, and the Schirmer 1 test.Results: The study included 257 subjects (94 LVC, 80 ICL, 83 control). The frequency of hyperosmolarity was significantly higher in the LVC group vs the control (73% vs 50%, p = 0.002), In contrast, the frequency of subjective symptoms tended to be lower in the LVC group than in the control group (19% vs 31%; p = 0.06). These differences were not seen between the ICL and control group.Conclusion: The results suggest that LVC may cause tear film instability as indicated by hyperosmolar tears up to 15 years after surgery, with few subjective symptoms of dry eye. This may have implications for IOL calculations for cataract or refractive lens exchange later in life.Keywords: tear film, hyperosmolarity, OSDI, post LVCGjerdrum BGundersen KGLundmark POPotvin RAakre BMDove Medical Pressarticletear filmhyperosmolarityosdipost lvcOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 14, Pp 269-279 (2020)
institution DOAJ
collection DOAJ
language EN
topic tear film
hyperosmolarity
osdi
post lvc
Ophthalmology
RE1-994
spellingShingle tear film
hyperosmolarity
osdi
post lvc
Ophthalmology
RE1-994
Gjerdrum B
Gundersen KG
Lundmark PO
Potvin R
Aakre BM
Prevalence of Signs and Symptoms of Dry Eye Disease 5 to 15 After Refractive Surgery
description Bjørn Gjerdrum,1,2 Kjell Gunnar Gundersen,2 Per Olof Lundmark,1 Rick Potvin,3 Bente Monica Aakre1 1Department of Optometry, Radiography and Lighting Design, University of South-Eastern Norway, Kongsberg, Norway; 2Ifocus Eye Clinic, Haugesund, Norway; 3Science in Vision, Akron, NY, USACorrespondence: Bjørn Gjerdrum Brønngata 36, Stavanger 4008, NorwayTel +47 415 11 935Email bjorn@ifocus.noPurpose: To compare the prevalence of dry eye disease (DED) as determined by signs and symptoms in patients with a history of laser vision correction (LVC) or implantable collamer lens (ICL) implantation 5– 15 years ago with a matched control group with no history of refractive surgery.Patient and Methods: This was a cross-sectional case-control study. The subject population included patients who had LVC or ICL 5 to 15 years ago. The control group was age matched. A test eye was randomly chosen. Subjects were required to have good ocular health. DED was evaluated using categorical cut-off criteria for tear film osmolarity (measured in both eyes), the subjective Ocular Surface Disease Index (OSDI), the dynamic Objective Scatter Index (OSI), non-invasive keratography tear break-up time (NIKBUT), meibography, and the Schirmer 1 test.Results: The study included 257 subjects (94 LVC, 80 ICL, 83 control). The frequency of hyperosmolarity was significantly higher in the LVC group vs the control (73% vs 50%, p = 0.002), In contrast, the frequency of subjective symptoms tended to be lower in the LVC group than in the control group (19% vs 31%; p = 0.06). These differences were not seen between the ICL and control group.Conclusion: The results suggest that LVC may cause tear film instability as indicated by hyperosmolar tears up to 15 years after surgery, with few subjective symptoms of dry eye. This may have implications for IOL calculations for cataract or refractive lens exchange later in life.Keywords: tear film, hyperosmolarity, OSDI, post LVC
format article
author Gjerdrum B
Gundersen KG
Lundmark PO
Potvin R
Aakre BM
author_facet Gjerdrum B
Gundersen KG
Lundmark PO
Potvin R
Aakre BM
author_sort Gjerdrum B
title Prevalence of Signs and Symptoms of Dry Eye Disease 5 to 15 After Refractive Surgery
title_short Prevalence of Signs and Symptoms of Dry Eye Disease 5 to 15 After Refractive Surgery
title_full Prevalence of Signs and Symptoms of Dry Eye Disease 5 to 15 After Refractive Surgery
title_fullStr Prevalence of Signs and Symptoms of Dry Eye Disease 5 to 15 After Refractive Surgery
title_full_unstemmed Prevalence of Signs and Symptoms of Dry Eye Disease 5 to 15 After Refractive Surgery
title_sort prevalence of signs and symptoms of dry eye disease 5 to 15 after refractive surgery
publisher Dove Medical Press
publishDate 2020
url https://doaj.org/article/6d39af6310a24fcbb945fc2747447ae8
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