Photoredox-catalyzed branch-selective pyridylation of alkenes for the expedient synthesis of Triprolidine
Alkenylpyridines are versatile building blocks for the synthesis of drugs and other complex molecular structures. Here, the authors show a branch-selective pyridylation of alkenes via sulfinate-assisted photoredox catalysis and showcase its utility in an expedient synthesis of Triprolidine.
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| Main Authors: | , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2019
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| Subjects: | |
| Online Access: | https://doaj.org/article/6d40b876cb7e4c64b129ff5e1e8b18a8 |
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| Summary: | Alkenylpyridines are versatile building blocks for the synthesis of drugs and other complex molecular structures. Here, the authors show a branch-selective pyridylation of alkenes via sulfinate-assisted photoredox catalysis and showcase its utility in an expedient synthesis of Triprolidine. |
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