Sept8/SEPTIN8 involvement in cellular structure and kidney damage is identified by genetic mapping and a novel human tubule hypoxic model

Sept8/SEPTIN8 involvement in cellular structure and kidney damage is identified by genetic mapping and a novel human tubule hypoxic model

Abstract Chronic kidney disease (CKD), which can ultimately progress to kidney failure, is influenced by genetics and the environment. Genes identified in human genome wide association studies (GWAS) explain only a small proportion of the heritable variation and lack functional validation, indicatin...

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Bibliographic Details
Main Authors: Gregory R. Keele, Jeremy W. Prokop, Hong He, Katie Holl, John Littrell, Aaron W. Deal, Yunjung Kim, Patrick B. Kyle, Esinam Attipoe, Ashley C. Johnson, Katie L. Uhl, Olivia L. Sirpilla, Seyedehameneh Jahanbakhsh, Melanie Robinson, Shawn Levy, William Valdar, Michael R. Garrett, Leah C. Solberg Woods
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/6d41003b7a614d5f9d1574c3f69d76e1
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