Psychiatric disorders in primary focal dystonia and in Parkinson’s disease
Fernando MV Dias1, Arthur Kummer1, Flávia CP Doyle2, Estefânia Harsányi1, Francisco Cardoso2, Leonardo F Fontenelle3, Antônio Lúcio Teixeira11Neuropsychiatric Branch, 2Movement Disorders Clinic, Neurology Unit, University Hospi...
Guardado en:
| Autores principales: | , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Dove Medical Press
2011
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/6d437ae91f954e85be0b8757bfe64573 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:6d437ae91f954e85be0b8757bfe64573 |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:6d437ae91f954e85be0b8757bfe645732021-12-02T02:57:16ZPsychiatric disorders in primary focal dystonia and in Parkinson’s disease1176-63281178-2021https://doaj.org/article/6d437ae91f954e85be0b8757bfe645732011-03-01T00:00:00Zhttp://www.dovepress.com/psychiatric-disorders-in-primary-focal-dystonia-and-in-parkinsonrsquos-a6679https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Fernando MV Dias1, Arthur Kummer1, Flávia CP Doyle2, Estefânia Harsányi1, Francisco Cardoso2, Leonardo F Fontenelle3, Antônio Lúcio Teixeira11Neuropsychiatric Branch, 2Movement Disorders Clinic, Neurology Unit, University Hospital, Federal University of Minas Gerais, Belo Horizonte; 3Department of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, BrazilBackground: Primary focal dystonia and Parkinson’s disease are movement disorders that have contrasting motor phenotypes. The aim of this study was to compare the frequency and the severity of psychiatric disorders in primary focal dystonia and Parkinson's disease.Methods: Two groups of 30 patients matched by gender and age underwent a neurological and psychiatric assessment.Results: Parkinson’s disease patients were diagnosed with higher rates of major depression (P = 0.02) and generalized anxiety disorder (P = 0.02), and greater severity of depressive symptoms (P = 0.04), while patients with primary focal dystonia exhibited increased severity of obsessive-compulsive symptoms (P = 0.02).Discussion: The difference in pathophysiology of primary focal dystonia and Parkinson’s disease may explain the different psychiatric profiles of these two diseases. The increased frequency of affective symptoms in Parkinson’s disease may be related to the fact that Parkinson's disease is a neurodegenerative disease marked by the loss of monoaminergic neurons which does not happen in primary focal dystonia.Conclusion: The psychiatric profile differs in movement disorders with distinct neurobiological bases.Keywords: focal dystonia, Parkinson’s disease, neuropsychiatry, depression, obsessive-compulsive disorder Fernando MV DiasArthur KummerFlávia CP Doyleet alDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2011, Iss Issue 1, Pp 111-116 (2011) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 |
| spellingShingle |
Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Fernando MV Dias Arthur Kummer Flávia CP Doyle et al Psychiatric disorders in primary focal dystonia and in Parkinson’s disease |
| description |
Fernando MV Dias1, Arthur Kummer1, Flávia CP Doyle2, Estefânia Harsányi1, Francisco Cardoso2, Leonardo F Fontenelle3, Antônio Lúcio Teixeira11Neuropsychiatric Branch, 2Movement Disorders Clinic, Neurology Unit, University Hospital, Federal University of Minas Gerais, Belo Horizonte; 3Department of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, BrazilBackground: Primary focal dystonia and Parkinson’s disease are movement disorders that have contrasting motor phenotypes. The aim of this study was to compare the frequency and the severity of psychiatric disorders in primary focal dystonia and Parkinson's disease.Methods: Two groups of 30 patients matched by gender and age underwent a neurological and psychiatric assessment.Results: Parkinson’s disease patients were diagnosed with higher rates of major depression (P = 0.02) and generalized anxiety disorder (P = 0.02), and greater severity of depressive symptoms (P = 0.04), while patients with primary focal dystonia exhibited increased severity of obsessive-compulsive symptoms (P = 0.02).Discussion: The difference in pathophysiology of primary focal dystonia and Parkinson’s disease may explain the different psychiatric profiles of these two diseases. The increased frequency of affective symptoms in Parkinson’s disease may be related to the fact that Parkinson's disease is a neurodegenerative disease marked by the loss of monoaminergic neurons which does not happen in primary focal dystonia.Conclusion: The psychiatric profile differs in movement disorders with distinct neurobiological bases.Keywords: focal dystonia, Parkinson’s disease, neuropsychiatry, depression, obsessive-compulsive disorder |
| format |
article |
| author |
Fernando MV Dias Arthur Kummer Flávia CP Doyle et al |
| author_facet |
Fernando MV Dias Arthur Kummer Flávia CP Doyle et al |
| author_sort |
Fernando MV Dias |
| title |
Psychiatric disorders in primary focal dystonia and in Parkinson’s disease |
| title_short |
Psychiatric disorders in primary focal dystonia and in Parkinson’s disease |
| title_full |
Psychiatric disorders in primary focal dystonia and in Parkinson’s disease |
| title_fullStr |
Psychiatric disorders in primary focal dystonia and in Parkinson’s disease |
| title_full_unstemmed |
Psychiatric disorders in primary focal dystonia and in Parkinson’s disease |
| title_sort |
psychiatric disorders in primary focal dystonia and in parkinson’s disease |
| publisher |
Dove Medical Press |
| publishDate |
2011 |
| url |
https://doaj.org/article/6d437ae91f954e85be0b8757bfe64573 |
| work_keys_str_mv |
AT fernandomvdias psychiatricdisordersinprimaryfocaldystoniaandinparkinsonamprsquosdisease AT arthurkummer psychiatricdisordersinprimaryfocaldystoniaandinparkinsonamprsquosdisease AT flampaacuteviacpdoyle psychiatricdisordersinprimaryfocaldystoniaandinparkinsonamprsquosdisease AT etal psychiatricdisordersinprimaryfocaldystoniaandinparkinsonamprsquosdisease |
| _version_ |
1718402046232625152 |