DIAGNOSIS OF HEMODYNAMIC CHANGES OF THE LIVER IN CONDITIONS OF BILIARY HYPERTENSION WITH PERFUSION COMPUTED TOMOGRAPHY

Diagnosis and treatment of patients with obstructive jaundice syndrome is one of the actual problems of abdominal surgery. The aim of our study was to determine criteria for the development of adverse outcomes in patients with obstructive jaundice, according to CT perfusion. We have analyzed the res...

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Autores principales:	V. A. Malakhanov, P. V. Seliverstov
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2017
Materias:	obstructive jaundice ct perfusion biliary decompression Science Q
Acceso en línea:	https://doaj.org/article/6d504781fc704a6382635d9f9186e590
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spelling	oai:doaj.org-article:6d504781fc704a6382635d9f9186e5902021-11-23T06:14:39ZDIAGNOSIS OF HEMODYNAMIC CHANGES OF THE LIVER IN CONDITIONS OF BILIARY HYPERTENSION WITH PERFUSION COMPUTED TOMOGRAPHY2541-94202587-959610.12737/article_5a0a8c9a61c014.61776297https://doaj.org/article/6d504781fc704a6382635d9f9186e5902017-11-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/485https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Diagnosis and treatment of patients with obstructive jaundice syndrome is one of the actual problems of abdominal surgery. The aim of our study was to determine criteria for the development of adverse outcomes in patients with obstructive jaundice, according to CT perfusion. We have analyzed the results of perfusion CT of 47 patients with mechanical jaundice syndrome. All patients were divided into two groups according to severity of the process. The first group (mild) included 29 patients with jaundice duration up to 7 days and the level of total bilirubin up to 150.0 mmol/L. The second group (moderate) included 18 patients with a duration of the disease of more than 7 days and the level of bilirubin more 150.0 mmol/L. Analysis of perfusion CT results showed that in the group of patients with mild jaundice, significant changes in arterial and portal hemodynamics do not occur. In patients in the second group, we revealed expressed reduction of portal hemodynamics up to 50.0 % (p < 0.003). ALP and HPI were increased twofold (p < 0.01). Despite increased arterial fraction, TLP reduced to 25.5 % (p < 0.05). When analyzing the postoperative complications, we observed the development of adverse outcomes only in patients with moderate degree of the pathology. When assessing the perfusion of the liver in patients with adverse outcomes compared with the control group there is a more pronounced decrease in PVP to 68.0% and TLP - up to 40.0% (p < 0.05).V. A. MalakhanovP. V. SeliverstovScientific Сentre for Family Health and Human Reproduction Problemsarticleobstructive jaundicect perfusionbiliary decompressionScienceQRUActa Biomedica Scientifica, Vol 2, Iss 6, Pp 137-141 (2017)
institution	DOAJ
collection	DOAJ
language	RU
topic	obstructive jaundice ct perfusion biliary decompression Science Q
spellingShingle	obstructive jaundice ct perfusion biliary decompression Science Q V. A. Malakhanov P. V. Seliverstov DIAGNOSIS OF HEMODYNAMIC CHANGES OF THE LIVER IN CONDITIONS OF BILIARY HYPERTENSION WITH PERFUSION COMPUTED TOMOGRAPHY
description	Diagnosis and treatment of patients with obstructive jaundice syndrome is one of the actual problems of abdominal surgery. The aim of our study was to determine criteria for the development of adverse outcomes in patients with obstructive jaundice, according to CT perfusion. We have analyzed the results of perfusion CT of 47 patients with mechanical jaundice syndrome. All patients were divided into two groups according to severity of the process. The first group (mild) included 29 patients with jaundice duration up to 7 days and the level of total bilirubin up to 150.0 mmol/L. The second group (moderate) included 18 patients with a duration of the disease of more than 7 days and the level of bilirubin more 150.0 mmol/L. Analysis of perfusion CT results showed that in the group of patients with mild jaundice, significant changes in arterial and portal hemodynamics do not occur. In patients in the second group, we revealed expressed reduction of portal hemodynamics up to 50.0 % (p < 0.003). ALP and HPI were increased twofold (p < 0.01). Despite increased arterial fraction, TLP reduced to 25.5 % (p < 0.05). When analyzing the postoperative complications, we observed the development of adverse outcomes only in patients with moderate degree of the pathology. When assessing the perfusion of the liver in patients with adverse outcomes compared with the control group there is a more pronounced decrease in PVP to 68.0% and TLP - up to 40.0% (p < 0.05).
format	article
author	V. A. Malakhanov P. V. Seliverstov
author_facet	V. A. Malakhanov P. V. Seliverstov
author_sort	V. A. Malakhanov
title	DIAGNOSIS OF HEMODYNAMIC CHANGES OF THE LIVER IN CONDITIONS OF BILIARY HYPERTENSION WITH PERFUSION COMPUTED TOMOGRAPHY
title_short	DIAGNOSIS OF HEMODYNAMIC CHANGES OF THE LIVER IN CONDITIONS OF BILIARY HYPERTENSION WITH PERFUSION COMPUTED TOMOGRAPHY
title_full	DIAGNOSIS OF HEMODYNAMIC CHANGES OF THE LIVER IN CONDITIONS OF BILIARY HYPERTENSION WITH PERFUSION COMPUTED TOMOGRAPHY
title_fullStr	DIAGNOSIS OF HEMODYNAMIC CHANGES OF THE LIVER IN CONDITIONS OF BILIARY HYPERTENSION WITH PERFUSION COMPUTED TOMOGRAPHY
title_full_unstemmed	DIAGNOSIS OF HEMODYNAMIC CHANGES OF THE LIVER IN CONDITIONS OF BILIARY HYPERTENSION WITH PERFUSION COMPUTED TOMOGRAPHY
title_sort	diagnosis of hemodynamic changes of the liver in conditions of biliary hypertension with perfusion computed tomography
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2017
url	https://doaj.org/article/6d504781fc704a6382635d9f9186e590
work_keys_str_mv	AT vamalakhanov diagnosisofhemodynamicchangesoftheliverinconditionsofbiliaryhypertensionwithperfusioncomputedtomography AT pvseliverstov diagnosisofhemodynamicchangesoftheliverinconditionsofbiliaryhypertensionwithperfusioncomputedtomography
_version_	1718417012330332160

DIAGNOSIS OF HEMODYNAMIC CHANGES OF THE LIVER IN CONDITIONS OF BILIARY HYPERTENSION WITH PERFUSION COMPUTED TOMOGRAPHY

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