Identifying determinants of cullin binding specificity among the three functionally different Drosophila melanogaster Roc proteins via domain swapping.
<h4>Background</h4>Cullin-dependent E3 ubiquitin ligases (CDL) are key regulators of protein destruction that participate in a wide range of cell biological processes. The Roc subunit of CDL contains an evolutionarily conserved RING domain that binds ubiquitin charged E2 and is essential...
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| Autores principales: | , , |
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| Formato: | article |
| Lenguaje: | EN |
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Public Library of Science (PLoS)
2008
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| Acceso en línea: | https://doaj.org/article/6d56f6ad72c94c2abb53277109422d55 |
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