Pulmonary Complications in Children Following Hematopoietic Cell Transplantation: A Case Report and Review of the Diagnostic Approach

Pulmonary complications are common in children following hematopoietic cell transplantation (HCT) and contribute to their morbidity and mortality. Early diagnosis is essential for management and prevention of progression of lung injury and damage. In many cases, diagnosis can be challenging and may...

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Autores principales:	Lama Elbahlawan, Jenny McArthur, Cara E. Morin, Hafeez Abdelhafeez, M. Beth McCarville, Robert E. Ruiz, Saumini Srinivasan, Amr Qudeimat
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	pulmonary complications hematopoietic (Stem) cell transplantation (HCT) lung biopsy broncho alveolar lavage (BAL) diagnostic approach diagnostic imaging Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/6d60a2c6aa1d41c2937c7e20d081886e
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spelling	oai:doaj.org-article:6d60a2c6aa1d41c2937c7e20d081886e2021-11-08T06:56:19ZPulmonary Complications in Children Following Hematopoietic Cell Transplantation: A Case Report and Review of the Diagnostic Approach2234-943X10.3389/fonc.2021.772411https://doaj.org/article/6d60a2c6aa1d41c2937c7e20d081886e2021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fonc.2021.772411/fullhttps://doaj.org/toc/2234-943XPulmonary complications are common in children following hematopoietic cell transplantation (HCT) and contribute to their morbidity and mortality. Early diagnosis is essential for management and prevention of progression of lung injury and damage. In many cases, diagnosis can be challenging and may require diagnostic imaging and more invasive testing such as bronchoscopy and lung biopsy. We report the case of a 12-year-old girl who developed recurrent episodes of acute respiratory failure requiring intensive care unit admission in the post-HCT phase and describe the diagnostic and multidisciplinary approach for her management. In addition, we review the diagnostic approach of pulmonary complications post-HCT and highlight the utility and risks of bronchoscopy and lung biopsy in these children.Lama ElbahlawanJenny McArthurCara E. MorinHafeez AbdelhafeezM. Beth McCarvilleRobert E. RuizSaumini SrinivasanAmr QudeimatFrontiers Media S.A.articlepulmonary complicationshematopoietic (Stem) cell transplantation (HCT)lung biopsybroncho alveolar lavage (BAL)diagnostic approachdiagnostic imagingNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENFrontiers in Oncology, Vol 11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	pulmonary complications hematopoietic (Stem) cell transplantation (HCT) lung biopsy broncho alveolar lavage (BAL) diagnostic approach diagnostic imaging Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	pulmonary complications hematopoietic (Stem) cell transplantation (HCT) lung biopsy broncho alveolar lavage (BAL) diagnostic approach diagnostic imaging Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Lama Elbahlawan Jenny McArthur Cara E. Morin Hafeez Abdelhafeez M. Beth McCarville Robert E. Ruiz Saumini Srinivasan Amr Qudeimat Pulmonary Complications in Children Following Hematopoietic Cell Transplantation: A Case Report and Review of the Diagnostic Approach
description	Pulmonary complications are common in children following hematopoietic cell transplantation (HCT) and contribute to their morbidity and mortality. Early diagnosis is essential for management and prevention of progression of lung injury and damage. In many cases, diagnosis can be challenging and may require diagnostic imaging and more invasive testing such as bronchoscopy and lung biopsy. We report the case of a 12-year-old girl who developed recurrent episodes of acute respiratory failure requiring intensive care unit admission in the post-HCT phase and describe the diagnostic and multidisciplinary approach for her management. In addition, we review the diagnostic approach of pulmonary complications post-HCT and highlight the utility and risks of bronchoscopy and lung biopsy in these children.
format	article
author	Lama Elbahlawan Jenny McArthur Cara E. Morin Hafeez Abdelhafeez M. Beth McCarville Robert E. Ruiz Saumini Srinivasan Amr Qudeimat
author_facet	Lama Elbahlawan Jenny McArthur Cara E. Morin Hafeez Abdelhafeez M. Beth McCarville Robert E. Ruiz Saumini Srinivasan Amr Qudeimat
author_sort	Lama Elbahlawan
title	Pulmonary Complications in Children Following Hematopoietic Cell Transplantation: A Case Report and Review of the Diagnostic Approach
title_short	Pulmonary Complications in Children Following Hematopoietic Cell Transplantation: A Case Report and Review of the Diagnostic Approach
title_full	Pulmonary Complications in Children Following Hematopoietic Cell Transplantation: A Case Report and Review of the Diagnostic Approach
title_fullStr	Pulmonary Complications in Children Following Hematopoietic Cell Transplantation: A Case Report and Review of the Diagnostic Approach
title_full_unstemmed	Pulmonary Complications in Children Following Hematopoietic Cell Transplantation: A Case Report and Review of the Diagnostic Approach
title_sort	pulmonary complications in children following hematopoietic cell transplantation: a case report and review of the diagnostic approach
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/6d60a2c6aa1d41c2937c7e20d081886e
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Pulmonary Complications in Children Following Hematopoietic Cell Transplantation: A Case Report and Review of the Diagnostic Approach

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