To target Tau pathologies, we must embrace and reconstruct their complexities

The accumulation of hyperphosphorylated fibrillar Tau aggregates in the brain is one of the defining hallmarks of Tauopathy diseases, including Alzheimer's disease. However, the primary events or molecules responsible for initiation of the pathological Tau aggregation and spreading remain unkno...

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Bibliographic Details
Main Authors: Galina Limorenko, Hilal A. Lashuel
Format: article
Language:EN
Published: Elsevier 2021
Subjects:
Tau
PHF
Online Access:https://doaj.org/article/6d694644510743b0955d7a5792a40587
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