N501Y mutation of spike protein in SARS-CoV-2 strengthens its binding to receptor ACE2
SARS-CoV-2 has been spreading around the world for the past year. Recently, several variants such as B.1.1.7 (alpha), B.1.351 (beta), and P.1 (gamma), which share a key mutation N501Y on the receptor-binding domain (RBD), appear to be more infectious to humans. To understand the underlying mechanism...
Guardado en:
Autores principales: | Fang Tian, Bei Tong, Liang Sun, Shengchao Shi, Bin Zheng, Zibin Wang, Xianchi Dong, Peng Zheng |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
eLife Sciences Publications Ltd
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/6d6d325ec0514285a12b3deb6ab193f0 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Force Dependence of Proteins’ Transition State Position and the Bell–Evans Model
por: Marc Rico-Pasto, et al.
Publicado: (2021) -
Structural Analysis on the Severe Acute Respiratory Syndrome Coronavirus 2 Non-structural Protein 13 Mutants Revealed Altered Bonding Network With TANK Binding Kinase 1 to Evade Host Immune System
por: Farooq Rashid, et al.
Publicado: (2021) -
The effect of N-glycosylation of SARS-CoV-2 spike protein on the virus interaction with the host cell ACE2 receptor
por: Chuncui Huang, et al.
Publicado: (2021) -
SARS-CoV-2 spike protein: Site-specific breakpoints for the development of COVID-19 vaccines
por: Palaniyandi Velusamy, et al.
Publicado: (2021) -
Archaeal Chromatin Proteins Cren7 and Sul7d Compact DNA by Bending and Bridging
por: Zhenfeng Zhang, et al.
Publicado: (2020)