A quantitative mass spectrometry-based approach to monitor the dynamics of endogenous chromatin-associated protein complexes

Chromatin-associated protein complexes play a critical role in the regulation of gene expression in health and disease. Here, the authors describe a sensitive mass spectrometry-based method to monitor the dynamic interactions of endogenous chromatin-associated protein complexes in clinical samples.

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Autores principales:	Evangelia K. Papachristou, Kamal Kishore, Andrew N. Holding, Kate Harvey, Theodoros I. Roumeliotis, Chandra Sekhar Reddy Chilamakuri, Soleilmane Omarjee, Kee Ming Chia, Alex Swarbrick, Elgene Lim, Florian Markowetz, Matthew Eldridge, Rasmus Siersbaek, Clive S. D’Santos, Jason S. Carroll
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6d77c38577f14fe9922378d351669816
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spelling	oai:doaj.org-article:6d77c38577f14fe9922378d3516698162021-12-02T15:34:28ZA quantitative mass spectrometry-based approach to monitor the dynamics of endogenous chromatin-associated protein complexes10.1038/s41467-018-04619-52041-1723https://doaj.org/article/6d77c38577f14fe9922378d3516698162018-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04619-5https://doaj.org/toc/2041-1723Chromatin-associated protein complexes play a critical role in the regulation of gene expression in health and disease. Here, the authors describe a sensitive mass spectrometry-based method to monitor the dynamic interactions of endogenous chromatin-associated protein complexes in clinical samples.Evangelia K. PapachristouKamal KishoreAndrew N. HoldingKate HarveyTheodoros I. RoumeliotisChandra Sekhar Reddy ChilamakuriSoleilmane OmarjeeKee Ming ChiaAlex SwarbrickElgene LimFlorian MarkowetzMatthew EldridgeRasmus SiersbaekClive S. D’SantosJason S. CarrollNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Evangelia K. Papachristou Kamal Kishore Andrew N. Holding Kate Harvey Theodoros I. Roumeliotis Chandra Sekhar Reddy Chilamakuri Soleilmane Omarjee Kee Ming Chia Alex Swarbrick Elgene Lim Florian Markowetz Matthew Eldridge Rasmus Siersbaek Clive S. D’Santos Jason S. Carroll A quantitative mass spectrometry-based approach to monitor the dynamics of endogenous chromatin-associated protein complexes
description	Chromatin-associated protein complexes play a critical role in the regulation of gene expression in health and disease. Here, the authors describe a sensitive mass spectrometry-based method to monitor the dynamic interactions of endogenous chromatin-associated protein complexes in clinical samples.
format	article
author	Evangelia K. Papachristou Kamal Kishore Andrew N. Holding Kate Harvey Theodoros I. Roumeliotis Chandra Sekhar Reddy Chilamakuri Soleilmane Omarjee Kee Ming Chia Alex Swarbrick Elgene Lim Florian Markowetz Matthew Eldridge Rasmus Siersbaek Clive S. D’Santos Jason S. Carroll
author_facet	Evangelia K. Papachristou Kamal Kishore Andrew N. Holding Kate Harvey Theodoros I. Roumeliotis Chandra Sekhar Reddy Chilamakuri Soleilmane Omarjee Kee Ming Chia Alex Swarbrick Elgene Lim Florian Markowetz Matthew Eldridge Rasmus Siersbaek Clive S. D’Santos Jason S. Carroll
author_sort	Evangelia K. Papachristou
title	A quantitative mass spectrometry-based approach to monitor the dynamics of endogenous chromatin-associated protein complexes
title_short	A quantitative mass spectrometry-based approach to monitor the dynamics of endogenous chromatin-associated protein complexes
title_full	A quantitative mass spectrometry-based approach to monitor the dynamics of endogenous chromatin-associated protein complexes
title_fullStr	A quantitative mass spectrometry-based approach to monitor the dynamics of endogenous chromatin-associated protein complexes
title_full_unstemmed	A quantitative mass spectrometry-based approach to monitor the dynamics of endogenous chromatin-associated protein complexes
title_sort	quantitative mass spectrometry-based approach to monitor the dynamics of endogenous chromatin-associated protein complexes
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/6d77c38577f14fe9922378d351669816
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A quantitative mass spectrometry-based approach to monitor the dynamics of endogenous chromatin-associated protein complexes

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