Rad-Bio-App: a discovery environment for biologists to explore spaceflight-related radiation exposures

In addition to microgravity, spaceflight simultaneously exposes biology to a suite of other stimuli. For example, in space, organisms experience ionizing radiation environments that significantly differ in both quality and quantity from those normally experienced on Earth. However, data on radiation...

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Autores principales:	Richard Barker, Sylvain V. Costes, Jack Miller, Samrawit G. Gebre, Jonathan Lombardino, Simon Gilroy
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biotechnology TP248.13-248.65 Physiology QP1-981
Acceso en línea:	https://doaj.org/article/6d7c792406b945fd9b935281d5421040
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id	oai:doaj.org-article:6d7c792406b945fd9b935281d5421040
record_format	dspace
spelling	oai:doaj.org-article:6d7c792406b945fd9b935281d54210402021-12-02T14:35:52ZRad-Bio-App: a discovery environment for biologists to explore spaceflight-related radiation exposures10.1038/s41526-021-00143-x2373-8065https://doaj.org/article/6d7c792406b945fd9b935281d54210402021-05-01T00:00:00Zhttps://doi.org/10.1038/s41526-021-00143-xhttps://doaj.org/toc/2373-8065In addition to microgravity, spaceflight simultaneously exposes biology to a suite of other stimuli. For example, in space, organisms experience ionizing radiation environments that significantly differ in both quality and quantity from those normally experienced on Earth. However, data on radiation exposure during space missions is often complex to access and to understand, limiting progress towards defining how radiation affects organisms against the unique background of spaceflight. To help address this challenge, we have developed the Rad-Bio-App. This web-accessible database imports radiation metadata from experiments archived in NASA’s GeneLab data repository, and then allows the user to explore these experiments both in the context of their radiation exposure and through their other metadata and results. Rad-Bio-App provides an easy-to-use, graphically-driven environment to enable both radiation biologists and non-specialist researchers to visualize, and understand the impact of ionizing radiation on various biological systems in the context of spaceflight.Richard BarkerSylvain V. CostesJack MillerSamrawit G. GebreJonathan LombardinoSimon GilroyNature PortfolioarticleBiotechnologyTP248.13-248.65PhysiologyQP1-981ENnpj Microgravity, Vol 7, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biotechnology TP248.13-248.65 Physiology QP1-981
spellingShingle	Biotechnology TP248.13-248.65 Physiology QP1-981 Richard Barker Sylvain V. Costes Jack Miller Samrawit G. Gebre Jonathan Lombardino Simon Gilroy Rad-Bio-App: a discovery environment for biologists to explore spaceflight-related radiation exposures
description	In addition to microgravity, spaceflight simultaneously exposes biology to a suite of other stimuli. For example, in space, organisms experience ionizing radiation environments that significantly differ in both quality and quantity from those normally experienced on Earth. However, data on radiation exposure during space missions is often complex to access and to understand, limiting progress towards defining how radiation affects organisms against the unique background of spaceflight. To help address this challenge, we have developed the Rad-Bio-App. This web-accessible database imports radiation metadata from experiments archived in NASA’s GeneLab data repository, and then allows the user to explore these experiments both in the context of their radiation exposure and through their other metadata and results. Rad-Bio-App provides an easy-to-use, graphically-driven environment to enable both radiation biologists and non-specialist researchers to visualize, and understand the impact of ionizing radiation on various biological systems in the context of spaceflight.
format	article
author	Richard Barker Sylvain V. Costes Jack Miller Samrawit G. Gebre Jonathan Lombardino Simon Gilroy
author_facet	Richard Barker Sylvain V. Costes Jack Miller Samrawit G. Gebre Jonathan Lombardino Simon Gilroy
author_sort	Richard Barker
title	Rad-Bio-App: a discovery environment for biologists to explore spaceflight-related radiation exposures
title_short	Rad-Bio-App: a discovery environment for biologists to explore spaceflight-related radiation exposures
title_full	Rad-Bio-App: a discovery environment for biologists to explore spaceflight-related radiation exposures
title_fullStr	Rad-Bio-App: a discovery environment for biologists to explore spaceflight-related radiation exposures
title_full_unstemmed	Rad-Bio-App: a discovery environment for biologists to explore spaceflight-related radiation exposures
title_sort	rad-bio-app: a discovery environment for biologists to explore spaceflight-related radiation exposures
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/6d7c792406b945fd9b935281d5421040
work_keys_str_mv	AT richardbarker radbioappadiscoveryenvironmentforbiologiststoexplorespaceflightrelatedradiationexposures AT sylvainvcostes radbioappadiscoveryenvironmentforbiologiststoexplorespaceflightrelatedradiationexposures AT jackmiller radbioappadiscoveryenvironmentforbiologiststoexplorespaceflightrelatedradiationexposures AT samrawitggebre radbioappadiscoveryenvironmentforbiologiststoexplorespaceflightrelatedradiationexposures AT jonathanlombardino radbioappadiscoveryenvironmentforbiologiststoexplorespaceflightrelatedradiationexposures AT simongilroy radbioappadiscoveryenvironmentforbiologiststoexplorespaceflightrelatedradiationexposures
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Rad-Bio-App: a discovery environment for biologists to explore spaceflight-related radiation exposures

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