Downregulation of CD40L–CD40 attenuates seizure susceptibility and severity of seizures
Abstract Unregulated neuro-inflammation mediates seizures in temporal lobe epilepsy (TLE). Our aim was to determine the effect of CD40–CD40L activation in experimental seizures. CD40 deficient mice (CD40KO) and control mice (wild type, WT) received pentenyltetrazole (PTZ) or pilocarpine to evaluate...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2021
|
| Subjects: | |
| Online Access: | https://doaj.org/article/6d9c70ea7a994ef1a75229f6d984d92f |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Be the first to leave a comment!