Condition-Specific Molecular Network Analysis Revealed That Flagellar Proteins Are Involved in Electron Transfer Processes of Shewanella piezotolerans WP3

Because of the ability to metabolize a large number of electron acceptors such as nitrate, nitrite, fumarate, and metal oxides, Shewanella species have attracted much attention in recent years. Generally, the use of these electron acceptors is mainly achieved through electron transfer proteins and t...

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Autores principales:	Dewu Ding, Meineng Wang, Meili Wu, Chengzhi Gan, Pu Wu
Formato:	article
Lenguaje:	EN
Publicado:	Hindawi - Cambridge University Press 2021
Materias:	Genetics QH426-470
Acceso en línea:	https://doaj.org/article/6da9fcdedb1f46cd87032e727dbc1a4b
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spelling	oai:doaj.org-article:6da9fcdedb1f46cd87032e727dbc1a4b2021-12-02T19:44:22ZCondition-Specific Molecular Network Analysis Revealed That Flagellar Proteins Are Involved in Electron Transfer Processes of Shewanella piezotolerans WP30016-67231469-507310.1155/2021/9953783https://doaj.org/article/6da9fcdedb1f46cd87032e727dbc1a4b2021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/9953783https://doaj.org/toc/0016-6723https://doaj.org/toc/1469-5073Because of the ability to metabolize a large number of electron acceptors such as nitrate, nitrite, fumarate, and metal oxides, Shewanella species have attracted much attention in recent years. Generally, the use of these electron acceptors is mainly achieved through electron transfer proteins and their interactions which will dynamically change across different environmental conditions in cells. Therefore, functional analysis of condition-specific molecular networks can reveal biological information on electron transfer processes. By integrating expression data and molecular networks, we constructed condition-specific molecular networks for Shewanella piezotolerans WP3. We then identified condition-specific key genes and studied their potential functions with an emphasis on their roles in electron transfer processes. Functional module analysis showed that different flagellar assembly modules appeared under these conditions and suggested that flagellar proteins are important for these conditions. We also identified the electron transfer modules underlying these various environmental conditions. The present results could help with screening electron transfer genes and understanding electron transfer processes under various environmental conditions for the Shewanella species.Dewu DingMeineng WangMeili WuChengzhi GanPu WuHindawi - Cambridge University PressarticleGeneticsQH426-470ENGenetics Research, Vol 2021 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Genetics QH426-470
spellingShingle	Genetics QH426-470 Dewu Ding Meineng Wang Meili Wu Chengzhi Gan Pu Wu Condition-Specific Molecular Network Analysis Revealed That Flagellar Proteins Are Involved in Electron Transfer Processes of Shewanella piezotolerans WP3
description	Because of the ability to metabolize a large number of electron acceptors such as nitrate, nitrite, fumarate, and metal oxides, Shewanella species have attracted much attention in recent years. Generally, the use of these electron acceptors is mainly achieved through electron transfer proteins and their interactions which will dynamically change across different environmental conditions in cells. Therefore, functional analysis of condition-specific molecular networks can reveal biological information on electron transfer processes. By integrating expression data and molecular networks, we constructed condition-specific molecular networks for Shewanella piezotolerans WP3. We then identified condition-specific key genes and studied their potential functions with an emphasis on their roles in electron transfer processes. Functional module analysis showed that different flagellar assembly modules appeared under these conditions and suggested that flagellar proteins are important for these conditions. We also identified the electron transfer modules underlying these various environmental conditions. The present results could help with screening electron transfer genes and understanding electron transfer processes under various environmental conditions for the Shewanella species.
format	article
author	Dewu Ding Meineng Wang Meili Wu Chengzhi Gan Pu Wu
author_facet	Dewu Ding Meineng Wang Meili Wu Chengzhi Gan Pu Wu
author_sort	Dewu Ding
title	Condition-Specific Molecular Network Analysis Revealed That Flagellar Proteins Are Involved in Electron Transfer Processes of Shewanella piezotolerans WP3
title_short	Condition-Specific Molecular Network Analysis Revealed That Flagellar Proteins Are Involved in Electron Transfer Processes of Shewanella piezotolerans WP3
title_full	Condition-Specific Molecular Network Analysis Revealed That Flagellar Proteins Are Involved in Electron Transfer Processes of Shewanella piezotolerans WP3
title_fullStr	Condition-Specific Molecular Network Analysis Revealed That Flagellar Proteins Are Involved in Electron Transfer Processes of Shewanella piezotolerans WP3
title_full_unstemmed	Condition-Specific Molecular Network Analysis Revealed That Flagellar Proteins Are Involved in Electron Transfer Processes of Shewanella piezotolerans WP3
title_sort	condition-specific molecular network analysis revealed that flagellar proteins are involved in electron transfer processes of shewanella piezotolerans wp3
publisher	Hindawi - Cambridge University Press
publishDate	2021
url	https://doaj.org/article/6da9fcdedb1f46cd87032e727dbc1a4b
work_keys_str_mv	AT dewuding conditionspecificmolecularnetworkanalysisrevealedthatflagellarproteinsareinvolvedinelectrontransferprocessesofshewanellapiezotoleranswp3 AT meinengwang conditionspecificmolecularnetworkanalysisrevealedthatflagellarproteinsareinvolvedinelectrontransferprocessesofshewanellapiezotoleranswp3 AT meiliwu conditionspecificmolecularnetworkanalysisrevealedthatflagellarproteinsareinvolvedinelectrontransferprocessesofshewanellapiezotoleranswp3 AT chengzhigan conditionspecificmolecularnetworkanalysisrevealedthatflagellarproteinsareinvolvedinelectrontransferprocessesofshewanellapiezotoleranswp3 AT puwu conditionspecificmolecularnetworkanalysisrevealedthatflagellarproteinsareinvolvedinelectrontransferprocessesofshewanellapiezotoleranswp3
_version_	1718376088508301312

Condition-Specific Molecular Network Analysis Revealed That Flagellar Proteins Are Involved in Electron Transfer Processes of Shewanella piezotolerans WP3

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