Vpu-Mediated Counteraction of Tetherin Is a Major Determinant of HIV-1 Interferon Resistance

Vpu-Mediated Counteraction of Tetherin Is a Major Determinant of HIV-1 Interferon Resistance

ABSTRACT Human immunodeficiency virus type 1 (HIV-1) groups M, N, O, and P are the result of independent zoonotic transmissions of simian immunodeficiency viruses (SIVs) infecting great apes in Africa. Among these, only Vpu proteins of pandemic HIV-1 group M strains evolved potent activity against t...

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Autores principales: Dorota Kmiec, Shilpa S. Iyer, Christina M. Stürzel, Daniel Sauter, Beatrice H. Hahn, Frank Kirchhoff
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2016
Materias:
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/6dae67beccce4aa2b37a5b00912b36fb
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