Utility of urinary markers in the assessment of renal dysfunction in familial glomerulonephritis in Dobermann dogs

Dobermann dogs are reportedly predisposed to familial glomerulonephropathy. Proteinuria is a hallmark of canine familial glomerular diseases. The identification of glomerular abnormalities in breeds so predisposed is of great importance in improving breeding policy. Therefore, markers that allow the...

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Autores principales:	Winiarczyk Dagmara, Adaszek Łukasz, Madany Jacek, Winiarczyk Mateusz, Winiarczyk Stanisław
Formato:	article
Lenguaje:	EN
Publicado:	Sciendo 2020
Materias:	dobermann dogs proteinuria renal dysfunction glomerulonephritis urinary markers Veterinary medicine SF600-1100
Acceso en línea:	https://doaj.org/article/6db1a514129448779a4aad271e4b760e
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spelling	oai:doaj.org-article:6db1a514129448779a4aad271e4b760e2021-12-05T14:11:08ZUtility of urinary markers in the assessment of renal dysfunction in familial glomerulonephritis in Dobermann dogs2450-860810.2478/jvetres-2020-0012https://doaj.org/article/6db1a514129448779a4aad271e4b760e2020-02-01T00:00:00Zhttps://doi.org/10.2478/jvetres-2020-0012https://doaj.org/toc/2450-8608Dobermann dogs are reportedly predisposed to familial glomerulonephropathy. Proteinuria is a hallmark of canine familial glomerular diseases. The identification of glomerular abnormalities in breeds so predisposed is of great importance in improving breeding policy. Therefore, markers that allow the detection and localisation of renal damage are needed. The purpose of this study was to investigate the urinary concentrations of immunoglobulin G (uIgG), retinol-binding protein (uRBP), and Tamm–Horsfall protein (uTHP) in a family of Dobermanns with proteinuria and compare these concentrations with the corresponding values in healthy controls.Winiarczyk DagmaraAdaszek ŁukaszMadany JacekWiniarczyk MateuszWiniarczyk StanisławSciendoarticledobermann dogsproteinuriarenal dysfunctionglomerulonephritisurinary markersVeterinary medicineSF600-1100ENJournal of Veterinary Research, Vol 64, Iss 1, Pp 181-186 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	dobermann dogs proteinuria renal dysfunction glomerulonephritis urinary markers Veterinary medicine SF600-1100
spellingShingle	dobermann dogs proteinuria renal dysfunction glomerulonephritis urinary markers Veterinary medicine SF600-1100 Winiarczyk Dagmara Adaszek Łukasz Madany Jacek Winiarczyk Mateusz Winiarczyk Stanisław Utility of urinary markers in the assessment of renal dysfunction in familial glomerulonephritis in Dobermann dogs
description	Dobermann dogs are reportedly predisposed to familial glomerulonephropathy. Proteinuria is a hallmark of canine familial glomerular diseases. The identification of glomerular abnormalities in breeds so predisposed is of great importance in improving breeding policy. Therefore, markers that allow the detection and localisation of renal damage are needed. The purpose of this study was to investigate the urinary concentrations of immunoglobulin G (uIgG), retinol-binding protein (uRBP), and Tamm–Horsfall protein (uTHP) in a family of Dobermanns with proteinuria and compare these concentrations with the corresponding values in healthy controls.
format	article
author	Winiarczyk Dagmara Adaszek Łukasz Madany Jacek Winiarczyk Mateusz Winiarczyk Stanisław
author_facet	Winiarczyk Dagmara Adaszek Łukasz Madany Jacek Winiarczyk Mateusz Winiarczyk Stanisław
author_sort	Winiarczyk Dagmara
title	Utility of urinary markers in the assessment of renal dysfunction in familial glomerulonephritis in Dobermann dogs
title_short	Utility of urinary markers in the assessment of renal dysfunction in familial glomerulonephritis in Dobermann dogs
title_full	Utility of urinary markers in the assessment of renal dysfunction in familial glomerulonephritis in Dobermann dogs
title_fullStr	Utility of urinary markers in the assessment of renal dysfunction in familial glomerulonephritis in Dobermann dogs
title_full_unstemmed	Utility of urinary markers in the assessment of renal dysfunction in familial glomerulonephritis in Dobermann dogs
title_sort	utility of urinary markers in the assessment of renal dysfunction in familial glomerulonephritis in dobermann dogs
publisher	Sciendo
publishDate	2020
url	https://doaj.org/article/6db1a514129448779a4aad271e4b760e
work_keys_str_mv	AT winiarczykdagmara utilityofurinarymarkersintheassessmentofrenaldysfunctioninfamilialglomerulonephritisindobermanndogs AT adaszekłukasz utilityofurinarymarkersintheassessmentofrenaldysfunctioninfamilialglomerulonephritisindobermanndogs AT madanyjacek utilityofurinarymarkersintheassessmentofrenaldysfunctioninfamilialglomerulonephritisindobermanndogs AT winiarczykmateusz utilityofurinarymarkersintheassessmentofrenaldysfunctioninfamilialglomerulonephritisindobermanndogs AT winiarczykstanisław utilityofurinarymarkersintheassessmentofrenaldysfunctioninfamilialglomerulonephritisindobermanndogs
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Utility of urinary markers in the assessment of renal dysfunction in familial glomerulonephritis in Dobermann dogs

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