Gut fungal dysbiosis correlates with reduced efficacy of fecal microbiota transplantation in Clostridium difficile infection

Gut fungal dysbiosis correlates with reduced efficacy of fecal microbiota transplantation in Clostridium difficile infection

Fecal microbiota transplantation (FMT) is effective in treating recurrent Clostridium difficile infection (CDI). Here, the authors show that the composition of the gut fungal microbiota of donors and recipients, and especially the abundance of Candida, correlates with FMT outcome in CDI patients.

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Detalles Bibliográficos
Autores principales: Tao Zuo, Sunny H. Wong, Chun Pan Cheung, Kelvin Lam, Rashid Lui, Kitty Cheung, Fen Zhang, Whitney Tang, Jessica Y. L. Ching, Justin C. Y. Wu, Paul K. S. Chan, Joseph J. Y. Sung, Jun Yu, Francis K. L. Chan, Siew C. Ng
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Science
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Acceso en línea:https://doaj.org/article/6db4d89a8097486585f01e1b1458962f
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Descripción
Sumario:Fecal microbiota transplantation (FMT) is effective in treating recurrent Clostridium difficile infection (CDI). Here, the authors show that the composition of the gut fungal microbiota of donors and recipients, and especially the abundance of Candida, correlates with FMT outcome in CDI patients.

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