Gut fungal dysbiosis correlates with reduced efficacy of fecal microbiota transplantation in Clostridium difficile infection
Fecal microbiota transplantation (FMT) is effective in treating recurrent Clostridium difficile infection (CDI). Here, the authors show that the composition of the gut fungal microbiota of donors and recipients, and especially the abundance of Candida, correlates with FMT outcome in CDI patients.
Guardado en:
| Autores principales: | , , , , , , , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2018
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/6db4d89a8097486585f01e1b1458962f |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:6db4d89a8097486585f01e1b1458962f |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:6db4d89a8097486585f01e1b1458962f2021-12-02T15:34:36ZGut fungal dysbiosis correlates with reduced efficacy of fecal microbiota transplantation in Clostridium difficile infection10.1038/s41467-018-06103-62041-1723https://doaj.org/article/6db4d89a8097486585f01e1b1458962f2018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06103-6https://doaj.org/toc/2041-1723Fecal microbiota transplantation (FMT) is effective in treating recurrent Clostridium difficile infection (CDI). Here, the authors show that the composition of the gut fungal microbiota of donors and recipients, and especially the abundance of Candida, correlates with FMT outcome in CDI patients.Tao ZuoSunny H. WongChun Pan CheungKelvin LamRashid LuiKitty CheungFen ZhangWhitney TangJessica Y. L. ChingJustin C. Y. WuPaul K. S. ChanJoseph J. Y. SungJun YuFrancis K. L. ChanSiew C. NgNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Tao Zuo Sunny H. Wong Chun Pan Cheung Kelvin Lam Rashid Lui Kitty Cheung Fen Zhang Whitney Tang Jessica Y. L. Ching Justin C. Y. Wu Paul K. S. Chan Joseph J. Y. Sung Jun Yu Francis K. L. Chan Siew C. Ng Gut fungal dysbiosis correlates with reduced efficacy of fecal microbiota transplantation in Clostridium difficile infection |
| description |
Fecal microbiota transplantation (FMT) is effective in treating recurrent Clostridium difficile infection (CDI). Here, the authors show that the composition of the gut fungal microbiota of donors and recipients, and especially the abundance of Candida, correlates with FMT outcome in CDI patients. |
| format |
article |
| author |
Tao Zuo Sunny H. Wong Chun Pan Cheung Kelvin Lam Rashid Lui Kitty Cheung Fen Zhang Whitney Tang Jessica Y. L. Ching Justin C. Y. Wu Paul K. S. Chan Joseph J. Y. Sung Jun Yu Francis K. L. Chan Siew C. Ng |
| author_facet |
Tao Zuo Sunny H. Wong Chun Pan Cheung Kelvin Lam Rashid Lui Kitty Cheung Fen Zhang Whitney Tang Jessica Y. L. Ching Justin C. Y. Wu Paul K. S. Chan Joseph J. Y. Sung Jun Yu Francis K. L. Chan Siew C. Ng |
| author_sort |
Tao Zuo |
| title |
Gut fungal dysbiosis correlates with reduced efficacy of fecal microbiota transplantation in Clostridium difficile infection |
| title_short |
Gut fungal dysbiosis correlates with reduced efficacy of fecal microbiota transplantation in Clostridium difficile infection |
| title_full |
Gut fungal dysbiosis correlates with reduced efficacy of fecal microbiota transplantation in Clostridium difficile infection |
| title_fullStr |
Gut fungal dysbiosis correlates with reduced efficacy of fecal microbiota transplantation in Clostridium difficile infection |
| title_full_unstemmed |
Gut fungal dysbiosis correlates with reduced efficacy of fecal microbiota transplantation in Clostridium difficile infection |
| title_sort |
gut fungal dysbiosis correlates with reduced efficacy of fecal microbiota transplantation in clostridium difficile infection |
| publisher |
Nature Portfolio |
| publishDate |
2018 |
| url |
https://doaj.org/article/6db4d89a8097486585f01e1b1458962f |
| work_keys_str_mv |
AT taozuo gutfungaldysbiosiscorrelateswithreducedefficacyoffecalmicrobiotatransplantationinclostridiumdifficileinfection AT sunnyhwong gutfungaldysbiosiscorrelateswithreducedefficacyoffecalmicrobiotatransplantationinclostridiumdifficileinfection AT chunpancheung gutfungaldysbiosiscorrelateswithreducedefficacyoffecalmicrobiotatransplantationinclostridiumdifficileinfection AT kelvinlam gutfungaldysbiosiscorrelateswithreducedefficacyoffecalmicrobiotatransplantationinclostridiumdifficileinfection AT rashidlui gutfungaldysbiosiscorrelateswithreducedefficacyoffecalmicrobiotatransplantationinclostridiumdifficileinfection AT kittycheung gutfungaldysbiosiscorrelateswithreducedefficacyoffecalmicrobiotatransplantationinclostridiumdifficileinfection AT fenzhang gutfungaldysbiosiscorrelateswithreducedefficacyoffecalmicrobiotatransplantationinclostridiumdifficileinfection AT whitneytang gutfungaldysbiosiscorrelateswithreducedefficacyoffecalmicrobiotatransplantationinclostridiumdifficileinfection AT jessicaylching gutfungaldysbiosiscorrelateswithreducedefficacyoffecalmicrobiotatransplantationinclostridiumdifficileinfection AT justincywu gutfungaldysbiosiscorrelateswithreducedefficacyoffecalmicrobiotatransplantationinclostridiumdifficileinfection AT paulkschan gutfungaldysbiosiscorrelateswithreducedefficacyoffecalmicrobiotatransplantationinclostridiumdifficileinfection AT josephjysung gutfungaldysbiosiscorrelateswithreducedefficacyoffecalmicrobiotatransplantationinclostridiumdifficileinfection AT junyu gutfungaldysbiosiscorrelateswithreducedefficacyoffecalmicrobiotatransplantationinclostridiumdifficileinfection AT francisklchan gutfungaldysbiosiscorrelateswithreducedefficacyoffecalmicrobiotatransplantationinclostridiumdifficileinfection AT siewcng gutfungaldysbiosiscorrelateswithreducedefficacyoffecalmicrobiotatransplantationinclostridiumdifficileinfection |
| _version_ |
1718386786474917888 |