Untuned broadband spiral micro-coils achieve sensitive multi-nuclear NMR TX/RX from microfluidic samples

Abstract The low frequency plateau in the frequency response of an untuned micro-resonator permits broadband radio-frequency reception, albeit at the expense of optimal signal-to-noise ratio for a particular nucleus. In this contribution we determine useful figures of merit for broadband micro-coils...

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Autores principales:	Hossein Davoodi, Nurdiana Nordin, Hirokazu Munakata, Jan G. Korvink, Neil MacKinnon, Vlad Badilita
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/6dbfe7cf1d3444e183f270c41c7d70c4
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spelling	oai:doaj.org-article:6dbfe7cf1d3444e183f270c41c7d70c42021-12-02T18:15:45ZUntuned broadband spiral micro-coils achieve sensitive multi-nuclear NMR TX/RX from microfluidic samples10.1038/s41598-021-87247-22045-2322https://doaj.org/article/6dbfe7cf1d3444e183f270c41c7d70c42021-04-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-87247-2https://doaj.org/toc/2045-2322Abstract The low frequency plateau in the frequency response of an untuned micro-resonator permits broadband radio-frequency reception, albeit at the expense of optimal signal-to-noise ratio for a particular nucleus. In this contribution we determine useful figures of merit for broadband micro-coils, and thereby explore the parametric design space towards acceptable simultaneous excitation and reception of a microfluidic sample over a wide frequency band ranging from 13C to 1H, i.e., 125–500 MHz in an 11.74 T magnet. The detector achieves 37% of the performance of a comparably sized, tuned and matched resonator, and a linewidth of 17 ppb using standard magnet shims. The use of broadband detectors circumvents numerous difficulties introduced by multi-resonant RF detector circuits, including sample loading effects on matching, channel isolation, and field distortion.Hossein DavoodiNurdiana NordinHirokazu MunakataJan G. KorvinkNeil MacKinnonVlad BadilitaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Hossein Davoodi Nurdiana Nordin Hirokazu Munakata Jan G. Korvink Neil MacKinnon Vlad Badilita Untuned broadband spiral micro-coils achieve sensitive multi-nuclear NMR TX/RX from microfluidic samples
description	Abstract The low frequency plateau in the frequency response of an untuned micro-resonator permits broadband radio-frequency reception, albeit at the expense of optimal signal-to-noise ratio for a particular nucleus. In this contribution we determine useful figures of merit for broadband micro-coils, and thereby explore the parametric design space towards acceptable simultaneous excitation and reception of a microfluidic sample over a wide frequency band ranging from 13C to 1H, i.e., 125–500 MHz in an 11.74 T magnet. The detector achieves 37% of the performance of a comparably sized, tuned and matched resonator, and a linewidth of 17 ppb using standard magnet shims. The use of broadband detectors circumvents numerous difficulties introduced by multi-resonant RF detector circuits, including sample loading effects on matching, channel isolation, and field distortion.
format	article
author	Hossein Davoodi Nurdiana Nordin Hirokazu Munakata Jan G. Korvink Neil MacKinnon Vlad Badilita
author_facet	Hossein Davoodi Nurdiana Nordin Hirokazu Munakata Jan G. Korvink Neil MacKinnon Vlad Badilita
author_sort	Hossein Davoodi
title	Untuned broadband spiral micro-coils achieve sensitive multi-nuclear NMR TX/RX from microfluidic samples
title_short	Untuned broadband spiral micro-coils achieve sensitive multi-nuclear NMR TX/RX from microfluidic samples
title_full	Untuned broadband spiral micro-coils achieve sensitive multi-nuclear NMR TX/RX from microfluidic samples
title_fullStr	Untuned broadband spiral micro-coils achieve sensitive multi-nuclear NMR TX/RX from microfluidic samples
title_full_unstemmed	Untuned broadband spiral micro-coils achieve sensitive multi-nuclear NMR TX/RX from microfluidic samples
title_sort	untuned broadband spiral micro-coils achieve sensitive multi-nuclear nmr tx/rx from microfluidic samples
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/6dbfe7cf1d3444e183f270c41c7d70c4
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Untuned broadband spiral micro-coils achieve sensitive multi-nuclear NMR TX/RX from microfluidic samples

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