The Beneficial Effects of Adding Magnesium Sulphate to General Anesthesia for Laparoscopic Sleeve Gastrectomy

Background: Obesity is a significant health issue. It was estimated that about 700 million were obese. Some call this trend the “New World Syndrome”. Aim of the work: The study aims to compare between intravenous injections of one to two grams of magnesium sulfate [MgSO4] in patients scheduled for e...

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Autores principales:	Mahmoud Gaballah Montasser Ali, Ayman Saleh Mohamed Ragab, Adel Al-Hady Ahmed Diab
Formato:	article
Lenguaje:	EN
Publicado:	Al-Azhar University, Faculty of Medicine (Damietta) 2021
Materias:	general anesthesia obesity magnesium sulphate laparoscopic sleeve gastrectomy Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/6dca0b1fc53c4a02a22c6bdec8e98013
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spelling	oai:doaj.org-article:6dca0b1fc53c4a02a22c6bdec8e980132021-12-02T14:10:53ZThe Beneficial Effects of Adding Magnesium Sulphate to General Anesthesia for Laparoscopic Sleeve Gastrectomy2636-41742682-378010.21608/ijma.2020.121320https://doaj.org/article/6dca0b1fc53c4a02a22c6bdec8e980132021-01-01T00:00:00Zhttps://ijma.journals.ekb.eg/article_121320_50c18d5792350a0fa493721c41b186cd.pdfhttps://doaj.org/toc/2636-4174https://doaj.org/toc/2682-3780Background: Obesity is a significant health issue. It was estimated that about 700 million were obese. Some call this trend the “New World Syndrome”. Aim of the work: The study aims to compare between intravenous injections of one to two grams of magnesium sulfate [MgSO4] in patients scheduled for elective laparoscopic sleeve gastrectomy. Patients and methods: It is a multicenter study, which included 800 patients who were scheduled for elective laparoscopic sleeve gastrectomy under general anesthesia; all patients were randomly grouped into two equal groups [n = 400]. The first group for one gram and the second group for two grams of MgSO4 over 10 minutes immediately after induction of anesthesia and before starting surgery. Then, all were assessed postoperatively for different variables. Results: The duration of full recovery was significantly shorter, intensive care unit admission and postoperative pain immediately after recovery till the end of the first 18 hours was lower in M2 when compared to the M1 group. Postoperative respiratory depression, nausea, and vomiting were significantly decreased. The number of early ambulation was significantly increased, while the length of stay was significantly reduced in the M2 group. Intraoperative bleeding and pain after 18 hours showed a non-significant difference between both groups. Postoperative bleeding was reported in two patients in the M2 group and returning to the operating room again within 6 hours and managed by blood transfusion and surgical laparoscopy. No patients suffered from deep vein thrombosis or any other complications. Conclusion: Adding MgSO4 to general anesthesia in laparoscopic sleeve gastrectomy had beneficial effects, which increased by increasing the dose from one to two grams.Mahmoud Gaballah Montasser AliAyman Saleh Mohamed RagabAdel Al-Hady Ahmed DiabAl-Azhar University, Faculty of Medicine (Damietta)articlegeneral anesthesiaobesitymagnesium sulphatelaparoscopicsleeve gastrectomyMedicine (General)R5-920ENInternational Journal of Medical Arts, Vol 3, Iss 1, Pp 989-904 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	general anesthesia obesity magnesium sulphate laparoscopic sleeve gastrectomy Medicine (General) R5-920
spellingShingle	general anesthesia obesity magnesium sulphate laparoscopic sleeve gastrectomy Medicine (General) R5-920 Mahmoud Gaballah Montasser Ali Ayman Saleh Mohamed Ragab Adel Al-Hady Ahmed Diab The Beneficial Effects of Adding Magnesium Sulphate to General Anesthesia for Laparoscopic Sleeve Gastrectomy
description	Background: Obesity is a significant health issue. It was estimated that about 700 million were obese. Some call this trend the “New World Syndrome”. Aim of the work: The study aims to compare between intravenous injections of one to two grams of magnesium sulfate [MgSO4] in patients scheduled for elective laparoscopic sleeve gastrectomy. Patients and methods: It is a multicenter study, which included 800 patients who were scheduled for elective laparoscopic sleeve gastrectomy under general anesthesia; all patients were randomly grouped into two equal groups [n = 400]. The first group for one gram and the second group for two grams of MgSO4 over 10 minutes immediately after induction of anesthesia and before starting surgery. Then, all were assessed postoperatively for different variables. Results: The duration of full recovery was significantly shorter, intensive care unit admission and postoperative pain immediately after recovery till the end of the first 18 hours was lower in M2 when compared to the M1 group. Postoperative respiratory depression, nausea, and vomiting were significantly decreased. The number of early ambulation was significantly increased, while the length of stay was significantly reduced in the M2 group. Intraoperative bleeding and pain after 18 hours showed a non-significant difference between both groups. Postoperative bleeding was reported in two patients in the M2 group and returning to the operating room again within 6 hours and managed by blood transfusion and surgical laparoscopy. No patients suffered from deep vein thrombosis or any other complications. Conclusion: Adding MgSO4 to general anesthesia in laparoscopic sleeve gastrectomy had beneficial effects, which increased by increasing the dose from one to two grams.
format	article
author	Mahmoud Gaballah Montasser Ali Ayman Saleh Mohamed Ragab Adel Al-Hady Ahmed Diab
author_facet	Mahmoud Gaballah Montasser Ali Ayman Saleh Mohamed Ragab Adel Al-Hady Ahmed Diab
author_sort	Mahmoud Gaballah Montasser Ali
title	The Beneficial Effects of Adding Magnesium Sulphate to General Anesthesia for Laparoscopic Sleeve Gastrectomy
title_short	The Beneficial Effects of Adding Magnesium Sulphate to General Anesthesia for Laparoscopic Sleeve Gastrectomy
title_full	The Beneficial Effects of Adding Magnesium Sulphate to General Anesthesia for Laparoscopic Sleeve Gastrectomy
title_fullStr	The Beneficial Effects of Adding Magnesium Sulphate to General Anesthesia for Laparoscopic Sleeve Gastrectomy
title_full_unstemmed	The Beneficial Effects of Adding Magnesium Sulphate to General Anesthesia for Laparoscopic Sleeve Gastrectomy
title_sort	beneficial effects of adding magnesium sulphate to general anesthesia for laparoscopic sleeve gastrectomy
publisher	Al-Azhar University, Faculty of Medicine (Damietta)
publishDate	2021
url	https://doaj.org/article/6dca0b1fc53c4a02a22c6bdec8e98013
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The Beneficial Effects of Adding Magnesium Sulphate to General Anesthesia for Laparoscopic Sleeve Gastrectomy

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