SNAREs define targeting specificity of trafficking vesicles by combinatorial interaction with tethering factors

Intracellular vesicle targeting is mediated by Rab GTPases that cooperate with phosphatidylinositides and SNARE proteins, which then facilitate membrane fusion. Here, the authors microinject artificial vesicles into HeLa cells and find that SNAREs play a more prominent role in targeting specificity...

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Auteurs principaux: Seiichi Koike, Reinhard Jahn
Format: article
Langue:EN
Publié: Nature Portfolio 2019
Sujets:
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Accès en ligne:https://doaj.org/article/6dd1376363bc458ab11ca7f21b655c37
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