Active-site plasticity revealed in the asymmetric dimer of AnPrx6 the 1-Cys peroxiredoxin and molecular chaperone from Anabaena sp. PCC 7120
Abstract Peroxiredoxins (Prxs) are vital regulators of intracellular reactive oxygen species levels in all living organisms. Their activity depends on one or two catalytically active cysteine residues, the peroxidatic Cys (CP) and, if present, the resolving Cys (CR). A detailed catalytic cycle has b...
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Autores principales: | Yogesh Mishra, Michael Hall, Roland Locmelis, Kwangho Nam, Christopher A. G. Söderberg, Patrik Storm, Neha Chaurasia, Lal Chand Rai, Stefan Jansson, Wolfgang P. Schröder, Uwe H. Sauer |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/6dd50dd40579437da29c2f089e3c0464 |
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