The impact of 3'UTR variants on differential expression of candidate cancer susceptibility genes.
Variants in regulatory regions are predicted to play an important role in disease susceptibility of common diseases. Polymorphisms mapping to microRNA (miRNA) binding sites have been shown to disrupt the ability of miRNAs to target genes resulting in differential mRNA and protein expression. Skin tu...
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Autores principales: | Laura E Skeeles, Jessica L Fleming, Kimberly L Mahler, Amanda Ewart Toland |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/6dd6bd9439734e0db44ec85f1ad03e86 |
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