PURINERGIC REGULATION OF BASIC PHYSIOLOGICAL AND PATHOLOGICAL PROCESSES

Purinergic signaling has been actively studied over recent years. It happens, due to its involvement in pathogenesis of various diseases and pathologies such as infectious and non-infectious inflammation, tumor growth, graft-versus-host disease, autoimmune disorders, cardiovascular calcification etc...

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Autores principales:	A. S. Golovkin, I. A. Asadullina, I. V. Kudryavtsev
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2018
Materias:	purinergic regulation cd39 cd73 atp adenosine Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/6dd90a338bfb4e17a9b932c85e24b151
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id	oai:doaj.org-article:6dd90a338bfb4e17a9b932c85e24b151
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spelling	oai:doaj.org-article:6dd90a338bfb4e17a9b932c85e24b1512021-11-18T08:03:47ZPURINERGIC REGULATION OF BASIC PHYSIOLOGICAL AND PATHOLOGICAL PROCESSES1563-06252313-741X10.15789/1563-0625-2018-4-463-476https://doaj.org/article/6dd90a338bfb4e17a9b932c85e24b1512018-06-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/1556https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XPurinergic signaling has been actively studied over recent years. It happens, due to its involvement in pathogenesis of various diseases and pathologies such as infectious and non-infectious inflammation, tumor growth, graft-versus-host disease, autoimmune disorders, cardiovascular calcification etc. It has been shown that the purinergic system mediates fine tuning of the immune cell populations, like as cytokine and chemokine secretion, elimination of intracellular pathogens and mechanisms of programmed cell death. Novel approaches to therapy and disease prevention are based on studies of appropriate developmental mechanisms, including role of purinergic system in their regulation. This review contains analysis of recent achievements elucidating the role of purinergic regulation in pathogenesis of basic pathological conditions and diseases, as well as trends in development of new therapeutic approaches based on present knowledge.A. S. GolovkinI. A. AsadullinaI. V. KudryavtsevSPb RAACIarticlepurinergic regulationcd39cd73atpadenosineImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 20, Iss 4, Pp 463-476 (2018)
institution	DOAJ
collection	DOAJ
language	RU
topic	purinergic regulation cd39 cd73 atp adenosine Immunologic diseases. Allergy RC581-607
spellingShingle	purinergic regulation cd39 cd73 atp adenosine Immunologic diseases. Allergy RC581-607 A. S. Golovkin I. A. Asadullina I. V. Kudryavtsev PURINERGIC REGULATION OF BASIC PHYSIOLOGICAL AND PATHOLOGICAL PROCESSES
description	Purinergic signaling has been actively studied over recent years. It happens, due to its involvement in pathogenesis of various diseases and pathologies such as infectious and non-infectious inflammation, tumor growth, graft-versus-host disease, autoimmune disorders, cardiovascular calcification etc. It has been shown that the purinergic system mediates fine tuning of the immune cell populations, like as cytokine and chemokine secretion, elimination of intracellular pathogens and mechanisms of programmed cell death. Novel approaches to therapy and disease prevention are based on studies of appropriate developmental mechanisms, including role of purinergic system in their regulation. This review contains analysis of recent achievements elucidating the role of purinergic regulation in pathogenesis of basic pathological conditions and diseases, as well as trends in development of new therapeutic approaches based on present knowledge.
format	article
author	A. S. Golovkin I. A. Asadullina I. V. Kudryavtsev
author_facet	A. S. Golovkin I. A. Asadullina I. V. Kudryavtsev
author_sort	A. S. Golovkin
title	PURINERGIC REGULATION OF BASIC PHYSIOLOGICAL AND PATHOLOGICAL PROCESSES
title_short	PURINERGIC REGULATION OF BASIC PHYSIOLOGICAL AND PATHOLOGICAL PROCESSES
title_full	PURINERGIC REGULATION OF BASIC PHYSIOLOGICAL AND PATHOLOGICAL PROCESSES
title_fullStr	PURINERGIC REGULATION OF BASIC PHYSIOLOGICAL AND PATHOLOGICAL PROCESSES
title_full_unstemmed	PURINERGIC REGULATION OF BASIC PHYSIOLOGICAL AND PATHOLOGICAL PROCESSES
title_sort	purinergic regulation of basic physiological and pathological processes
publisher	SPb RAACI
publishDate	2018
url	https://doaj.org/article/6dd90a338bfb4e17a9b932c85e24b151
work_keys_str_mv	AT asgolovkin purinergicregulationofbasicphysiologicalandpathologicalprocesses AT iaasadullina purinergicregulationofbasicphysiologicalandpathologicalprocesses AT ivkudryavtsev purinergicregulationofbasicphysiologicalandpathologicalprocesses
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PURINERGIC REGULATION OF BASIC PHYSIOLOGICAL AND PATHOLOGICAL PROCESSES

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