A scaffold lncRNA shapes the mitosis to meiosis switch

In fission yeast, the antagonistic RNA-binding proteins Mmi1 and Mei2 respectively promote and inhibit meiotic mRNA degradation during mitotic growth. Here the authors show that the lncRNA mamRNA scaffolds Mmi1 and Mei2 proteins to enable their mutual controls.

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Autores principales: Vedrana Andric, Alicia Nevers, Ditipriya Hazra, Sylvie Auxilien, Alexandra Menant, Marc Graille, Benoit Palancade, Mathieu Rougemaille
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/6ddfa8f1105c486a91070ee1f51cf5a5
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spelling oai:doaj.org-article:6ddfa8f1105c486a91070ee1f51cf5a52021-12-02T14:06:22ZA scaffold lncRNA shapes the mitosis to meiosis switch10.1038/s41467-021-21032-72041-1723https://doaj.org/article/6ddfa8f1105c486a91070ee1f51cf5a52021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21032-7https://doaj.org/toc/2041-1723In fission yeast, the antagonistic RNA-binding proteins Mmi1 and Mei2 respectively promote and inhibit meiotic mRNA degradation during mitotic growth. Here the authors show that the lncRNA mamRNA scaffolds Mmi1 and Mei2 proteins to enable their mutual controls.Vedrana AndricAlicia NeversDitipriya HazraSylvie AuxilienAlexandra MenantMarc GrailleBenoit PalancadeMathieu RougemailleNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Vedrana Andric
Alicia Nevers
Ditipriya Hazra
Sylvie Auxilien
Alexandra Menant
Marc Graille
Benoit Palancade
Mathieu Rougemaille
A scaffold lncRNA shapes the mitosis to meiosis switch
description In fission yeast, the antagonistic RNA-binding proteins Mmi1 and Mei2 respectively promote and inhibit meiotic mRNA degradation during mitotic growth. Here the authors show that the lncRNA mamRNA scaffolds Mmi1 and Mei2 proteins to enable their mutual controls.
format article
author Vedrana Andric
Alicia Nevers
Ditipriya Hazra
Sylvie Auxilien
Alexandra Menant
Marc Graille
Benoit Palancade
Mathieu Rougemaille
author_facet Vedrana Andric
Alicia Nevers
Ditipriya Hazra
Sylvie Auxilien
Alexandra Menant
Marc Graille
Benoit Palancade
Mathieu Rougemaille
author_sort Vedrana Andric
title A scaffold lncRNA shapes the mitosis to meiosis switch
title_short A scaffold lncRNA shapes the mitosis to meiosis switch
title_full A scaffold lncRNA shapes the mitosis to meiosis switch
title_fullStr A scaffold lncRNA shapes the mitosis to meiosis switch
title_full_unstemmed A scaffold lncRNA shapes the mitosis to meiosis switch
title_sort scaffold lncrna shapes the mitosis to meiosis switch
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/6ddfa8f1105c486a91070ee1f51cf5a5
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