A scaffold lncRNA shapes the mitosis to meiosis switch
In fission yeast, the antagonistic RNA-binding proteins Mmi1 and Mei2 respectively promote and inhibit meiotic mRNA degradation during mitotic growth. Here the authors show that the lncRNA mamRNA scaffolds Mmi1 and Mei2 proteins to enable their mutual controls.
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Nature Portfolio
2021
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oai:doaj.org-article:6ddfa8f1105c486a91070ee1f51cf5a52021-12-02T14:06:22ZA scaffold lncRNA shapes the mitosis to meiosis switch10.1038/s41467-021-21032-72041-1723https://doaj.org/article/6ddfa8f1105c486a91070ee1f51cf5a52021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21032-7https://doaj.org/toc/2041-1723In fission yeast, the antagonistic RNA-binding proteins Mmi1 and Mei2 respectively promote and inhibit meiotic mRNA degradation during mitotic growth. Here the authors show that the lncRNA mamRNA scaffolds Mmi1 and Mei2 proteins to enable their mutual controls.Vedrana AndricAlicia NeversDitipriya HazraSylvie AuxilienAlexandra MenantMarc GrailleBenoit PalancadeMathieu RougemailleNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021) |
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Science Q Vedrana Andric Alicia Nevers Ditipriya Hazra Sylvie Auxilien Alexandra Menant Marc Graille Benoit Palancade Mathieu Rougemaille A scaffold lncRNA shapes the mitosis to meiosis switch |
description |
In fission yeast, the antagonistic RNA-binding proteins Mmi1 and Mei2 respectively promote and inhibit meiotic mRNA degradation during mitotic growth. Here the authors show that the lncRNA mamRNA scaffolds Mmi1 and Mei2 proteins to enable their mutual controls. |
format |
article |
author |
Vedrana Andric Alicia Nevers Ditipriya Hazra Sylvie Auxilien Alexandra Menant Marc Graille Benoit Palancade Mathieu Rougemaille |
author_facet |
Vedrana Andric Alicia Nevers Ditipriya Hazra Sylvie Auxilien Alexandra Menant Marc Graille Benoit Palancade Mathieu Rougemaille |
author_sort |
Vedrana Andric |
title |
A scaffold lncRNA shapes the mitosis to meiosis switch |
title_short |
A scaffold lncRNA shapes the mitosis to meiosis switch |
title_full |
A scaffold lncRNA shapes the mitosis to meiosis switch |
title_fullStr |
A scaffold lncRNA shapes the mitosis to meiosis switch |
title_full_unstemmed |
A scaffold lncRNA shapes the mitosis to meiosis switch |
title_sort |
scaffold lncrna shapes the mitosis to meiosis switch |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/6ddfa8f1105c486a91070ee1f51cf5a5 |
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