Ist1 regulates ESCRT-III assembly and function during multivesicular endosome biogenesis in Caenorhabditis elegans embryos

During the oocyte-to-embryo transition in C. elegans, multivesicular endosomes (MVEs) are formed rapidly. Using live imaging and electron microscopy, the authors here show that the ESCRT-III subunit Ist1 is required for normal MVE biogenesis in the early C. elegans embryo.

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Autores principales: E. B. Frankel, Raakhee Shankar, James J. Moresco, John R. Yates, Niels Volkmann, Anjon Audhya
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/6de2ed8f5a704921b22ce0f43f48b07c
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spelling oai:doaj.org-article:6de2ed8f5a704921b22ce0f43f48b07c2021-12-02T17:06:29ZIst1 regulates ESCRT-III assembly and function during multivesicular endosome biogenesis in Caenorhabditis elegans embryos10.1038/s41467-017-01636-82041-1723https://doaj.org/article/6de2ed8f5a704921b22ce0f43f48b07c2017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01636-8https://doaj.org/toc/2041-1723During the oocyte-to-embryo transition in C. elegans, multivesicular endosomes (MVEs) are formed rapidly. Using live imaging and electron microscopy, the authors here show that the ESCRT-III subunit Ist1 is required for normal MVE biogenesis in the early C. elegans embryo.E. B. FrankelRaakhee ShankarJames J. MorescoJohn R. YatesNiels VolkmannAnjon AudhyaNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
E. B. Frankel
Raakhee Shankar
James J. Moresco
John R. Yates
Niels Volkmann
Anjon Audhya
Ist1 regulates ESCRT-III assembly and function during multivesicular endosome biogenesis in Caenorhabditis elegans embryos
description During the oocyte-to-embryo transition in C. elegans, multivesicular endosomes (MVEs) are formed rapidly. Using live imaging and electron microscopy, the authors here show that the ESCRT-III subunit Ist1 is required for normal MVE biogenesis in the early C. elegans embryo.
format article
author E. B. Frankel
Raakhee Shankar
James J. Moresco
John R. Yates
Niels Volkmann
Anjon Audhya
author_facet E. B. Frankel
Raakhee Shankar
James J. Moresco
John R. Yates
Niels Volkmann
Anjon Audhya
author_sort E. B. Frankel
title Ist1 regulates ESCRT-III assembly and function during multivesicular endosome biogenesis in Caenorhabditis elegans embryos
title_short Ist1 regulates ESCRT-III assembly and function during multivesicular endosome biogenesis in Caenorhabditis elegans embryos
title_full Ist1 regulates ESCRT-III assembly and function during multivesicular endosome biogenesis in Caenorhabditis elegans embryos
title_fullStr Ist1 regulates ESCRT-III assembly and function during multivesicular endosome biogenesis in Caenorhabditis elegans embryos
title_full_unstemmed Ist1 regulates ESCRT-III assembly and function during multivesicular endosome biogenesis in Caenorhabditis elegans embryos
title_sort ist1 regulates escrt-iii assembly and function during multivesicular endosome biogenesis in caenorhabditis elegans embryos
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/6de2ed8f5a704921b22ce0f43f48b07c
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