Ist1 regulates ESCRT-III assembly and function during multivesicular endosome biogenesis in Caenorhabditis elegans embryos

During the oocyte-to-embryo transition in C. elegans, multivesicular endosomes (MVEs) are formed rapidly. Using live imaging and electron microscopy, the authors here show that the ESCRT-III subunit Ist1 is required for normal MVE biogenesis in the early C. elegans embryo.

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Main Authors:	E. B. Frankel, Raakhee Shankar, James J. Moresco, John R. Yates, Niels Volkmann, Anjon Audhya
Format:	article
Language:	EN
Published:	Nature Portfolio 2017
Subjects:	Science Q
Online Access:	https://doaj.org/article/6de2ed8f5a704921b22ce0f43f48b07c
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spelling	oai:doaj.org-article:6de2ed8f5a704921b22ce0f43f48b07c2021-12-02T17:06:29ZIst1 regulates ESCRT-III assembly and function during multivesicular endosome biogenesis in Caenorhabditis elegans embryos10.1038/s41467-017-01636-82041-1723https://doaj.org/article/6de2ed8f5a704921b22ce0f43f48b07c2017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01636-8https://doaj.org/toc/2041-1723During the oocyte-to-embryo transition in C. elegans, multivesicular endosomes (MVEs) are formed rapidly. Using live imaging and electron microscopy, the authors here show that the ESCRT-III subunit Ist1 is required for normal MVE biogenesis in the early C. elegans embryo.E. B. FrankelRaakhee ShankarJames J. MorescoJohn R. YatesNiels VolkmannAnjon AudhyaNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q E. B. Frankel Raakhee Shankar James J. Moresco John R. Yates Niels Volkmann Anjon Audhya Ist1 regulates ESCRT-III assembly and function during multivesicular endosome biogenesis in Caenorhabditis elegans embryos
description	During the oocyte-to-embryo transition in C. elegans, multivesicular endosomes (MVEs) are formed rapidly. Using live imaging and electron microscopy, the authors here show that the ESCRT-III subunit Ist1 is required for normal MVE biogenesis in the early C. elegans embryo.
format	article
author	E. B. Frankel Raakhee Shankar James J. Moresco John R. Yates Niels Volkmann Anjon Audhya
author_facet	E. B. Frankel Raakhee Shankar James J. Moresco John R. Yates Niels Volkmann Anjon Audhya
author_sort	E. B. Frankel
title	Ist1 regulates ESCRT-III assembly and function during multivesicular endosome biogenesis in Caenorhabditis elegans embryos
title_short	Ist1 regulates ESCRT-III assembly and function during multivesicular endosome biogenesis in Caenorhabditis elegans embryos
title_full	Ist1 regulates ESCRT-III assembly and function during multivesicular endosome biogenesis in Caenorhabditis elegans embryos
title_fullStr	Ist1 regulates ESCRT-III assembly and function during multivesicular endosome biogenesis in Caenorhabditis elegans embryos
title_full_unstemmed	Ist1 regulates ESCRT-III assembly and function during multivesicular endosome biogenesis in Caenorhabditis elegans embryos
title_sort	ist1 regulates escrt-iii assembly and function during multivesicular endosome biogenesis in caenorhabditis elegans embryos
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/6de2ed8f5a704921b22ce0f43f48b07c
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_version_	1718381617165107200

Ist1 regulates ESCRT-III assembly and function during multivesicular endosome biogenesis in Caenorhabditis elegans embryos

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