Molecular Mechanisms of the Toll-Like Receptor, STING, MAVS, Inflammasome, and Interferon Pathways

Pattern recognition receptors (PRRs) form the front line of defense against pathogens. Many of the molecular mechanisms that facilitate PRR signaling have been characterized in detail, which is critical for the development of accurate PRR pathway models at the molecular interaction level.

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Autores principales: Nathan P. Manes, Aleksandra Nita-Lazar
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/6de57a808ac44dc58d7511e3293f1556
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spelling oai:doaj.org-article:6de57a808ac44dc58d7511e3293f15562021-12-02T18:48:31ZMolecular Mechanisms of the Toll-Like Receptor, STING, MAVS, Inflammasome, and Interferon Pathways2379-507710.1128/mSystems.00336-21https://doaj.org/article/6de57a808ac44dc58d7511e3293f15562021-06-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mSystems.00336-21https://doaj.org/toc/2379-5077 Pattern recognition receptors (PRRs) form the front line of defense against pathogens. Many of the molecular mechanisms that facilitate PRR signaling have been characterized in detail, which is critical for the development of accurate PRR pathway models at the molecular interaction level.Nathan P. ManesAleksandra Nita-LazarAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmSystems, Vol 6, Iss 3 (2021)
institution DOAJ
collection DOAJ
language EN
topic Microbiology
QR1-502
spellingShingle Microbiology
QR1-502
Nathan P. Manes
Aleksandra Nita-Lazar
Molecular Mechanisms of the Toll-Like Receptor, STING, MAVS, Inflammasome, and Interferon Pathways
description Pattern recognition receptors (PRRs) form the front line of defense against pathogens. Many of the molecular mechanisms that facilitate PRR signaling have been characterized in detail, which is critical for the development of accurate PRR pathway models at the molecular interaction level.
format article
author Nathan P. Manes
Aleksandra Nita-Lazar
author_facet Nathan P. Manes
Aleksandra Nita-Lazar
author_sort Nathan P. Manes
title Molecular Mechanisms of the Toll-Like Receptor, STING, MAVS, Inflammasome, and Interferon Pathways
title_short Molecular Mechanisms of the Toll-Like Receptor, STING, MAVS, Inflammasome, and Interferon Pathways
title_full Molecular Mechanisms of the Toll-Like Receptor, STING, MAVS, Inflammasome, and Interferon Pathways
title_fullStr Molecular Mechanisms of the Toll-Like Receptor, STING, MAVS, Inflammasome, and Interferon Pathways
title_full_unstemmed Molecular Mechanisms of the Toll-Like Receptor, STING, MAVS, Inflammasome, and Interferon Pathways
title_sort molecular mechanisms of the toll-like receptor, sting, mavs, inflammasome, and interferon pathways
publisher American Society for Microbiology
publishDate 2021
url https://doaj.org/article/6de57a808ac44dc58d7511e3293f1556
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