One-domain CD4 Fused to Human Anti-CD16 Antibody Domain Mediates Effective Killing of HIV-1-Infected Cells

One-domain CD4 Fused to Human Anti-CD16 Antibody Domain Mediates Effective Killing of HIV-1-Infected Cells

Abstract Bispecific killer cells engagers (BiKEs) which can bind to natural killer (NK) cells through the activating receptor CD16A and guide them to cells expressing the HIV-1 envelope glycoprotein (Env) are a promising new weapon for elimination of infected cells and eradication of the virus. Here...

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Autores principales: Wei Li, Yanling Wu, Desheng Kong, Hongjia Yang, Yanping Wang, Jiping Shao, Yang Feng, Weizao Chen, Liying Ma, Tianlei Ying, Dimiter S. Dimitrov
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/6de655539e6c4a1ab5f74ef528ceb372
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