Mechanisms and targets of Fcγ-receptor mediated immunity to malaria sporozoites

Antibodies plays critical roles in the adaptive immune response to infectious agents including malaria. Here the authors defined antibody interactions with -Fcγ-receptors expressed on immune cells with sporozoites of Plasmodium falciparum, and identified specific target epitopes of antibodies.

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Autores principales: Gaoqian Feng, Bruce D. Wines, Liriye Kurtovic, Jo-Anne Chan, Philippe Boeuf, Vanessa Mollard, Anton Cozijnsen, Damien R. Drew, Rob J. Center, Daniel L. Marshall, Sandra Chishimba, Geoffrey I. McFadden, Arlene E. Dent, Kiprotich Chelimo, Michelle J. Boyle, James W. Kazura, P. Mark Hogarth, James G. Beeson
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/6df085e64a2441099441e81ae6947fa5
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spelling oai:doaj.org-article:6df085e64a2441099441e81ae6947fa52021-12-02T13:17:40ZMechanisms and targets of Fcγ-receptor mediated immunity to malaria sporozoites10.1038/s41467-021-21998-42041-1723https://doaj.org/article/6df085e64a2441099441e81ae6947fa52021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21998-4https://doaj.org/toc/2041-1723Antibodies plays critical roles in the adaptive immune response to infectious agents including malaria. Here the authors defined antibody interactions with -Fcγ-receptors expressed on immune cells with sporozoites of Plasmodium falciparum, and identified specific target epitopes of antibodies.Gaoqian FengBruce D. WinesLiriye KurtovicJo-Anne ChanPhilippe BoeufVanessa MollardAnton CozijnsenDamien R. DrewRob J. CenterDaniel L. MarshallSandra ChishimbaGeoffrey I. McFaddenArlene E. DentKiprotich ChelimoMichelle J. BoyleJames W. KazuraP. Mark HogarthJames G. BeesonNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Gaoqian Feng
Bruce D. Wines
Liriye Kurtovic
Jo-Anne Chan
Philippe Boeuf
Vanessa Mollard
Anton Cozijnsen
Damien R. Drew
Rob J. Center
Daniel L. Marshall
Sandra Chishimba
Geoffrey I. McFadden
Arlene E. Dent
Kiprotich Chelimo
Michelle J. Boyle
James W. Kazura
P. Mark Hogarth
James G. Beeson
Mechanisms and targets of Fcγ-receptor mediated immunity to malaria sporozoites
description Antibodies plays critical roles in the adaptive immune response to infectious agents including malaria. Here the authors defined antibody interactions with -Fcγ-receptors expressed on immune cells with sporozoites of Plasmodium falciparum, and identified specific target epitopes of antibodies.
format article
author Gaoqian Feng
Bruce D. Wines
Liriye Kurtovic
Jo-Anne Chan
Philippe Boeuf
Vanessa Mollard
Anton Cozijnsen
Damien R. Drew
Rob J. Center
Daniel L. Marshall
Sandra Chishimba
Geoffrey I. McFadden
Arlene E. Dent
Kiprotich Chelimo
Michelle J. Boyle
James W. Kazura
P. Mark Hogarth
James G. Beeson
author_facet Gaoqian Feng
Bruce D. Wines
Liriye Kurtovic
Jo-Anne Chan
Philippe Boeuf
Vanessa Mollard
Anton Cozijnsen
Damien R. Drew
Rob J. Center
Daniel L. Marshall
Sandra Chishimba
Geoffrey I. McFadden
Arlene E. Dent
Kiprotich Chelimo
Michelle J. Boyle
James W. Kazura
P. Mark Hogarth
James G. Beeson
author_sort Gaoqian Feng
title Mechanisms and targets of Fcγ-receptor mediated immunity to malaria sporozoites
title_short Mechanisms and targets of Fcγ-receptor mediated immunity to malaria sporozoites
title_full Mechanisms and targets of Fcγ-receptor mediated immunity to malaria sporozoites
title_fullStr Mechanisms and targets of Fcγ-receptor mediated immunity to malaria sporozoites
title_full_unstemmed Mechanisms and targets of Fcγ-receptor mediated immunity to malaria sporozoites
title_sort mechanisms and targets of fcγ-receptor mediated immunity to malaria sporozoites
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/6df085e64a2441099441e81ae6947fa5
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