Circ-SIRT1 inhibits cardiac hypertrophy via activating SIRT1 to promote autophagy

Abstract Mounting studies have substantiated that abrogating autophagy contributes to cardiac hypertrophy (CH). Sirtuin 1 (SIRT1) has been reported to support autophagy and inhibit CH. However, the upstream regulation mechanism behind the regulation of SIRT1 level in CH remains unclear. Circular RNA...

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Bibliographic Details
Main Authors: Weichen Wang, Longlong Wang, Mengyue Yang, Chunwei Wu, Rui Lan, Weiwei Wang, Yuze Li
Format: article
Language:EN
Published: Nature Publishing Group 2021
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Online Access:https://doaj.org/article/6dfba9eb14e84524ac602a7cd1635ea5
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