Does electrical stimulation improve healing in acute minor burn injury, as measured by bioimpedance spectroscopy? A single center, randomized, controlled trial

Background: Electrical stimulation (ES) has been shown to improve wound healing in chronic wounds. Recent studies in burn injured populations have demonstrated that ES improved edema and healing using short duration stimulation. This study utilized a low energy long duration ES using a portable devi...

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Autores principales:	Dale O. Edwick, Dana A. Hince, Jeremy M. Rawlins, Fiona M. Wood, Dale W. Edgar
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2022
Materias:	Wound healing Bioelectrical impedance Electrical stimulation Burns Edema Dermatology RL1-803 Medical emergencies. Critical care. Intensive care. First aid RC86-88.9
Acceso en línea:	https://doaj.org/article/6dfc63275b8c4400b0f097b30536992f
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spelling	oai:doaj.org-article:6dfc63275b8c4400b0f097b30536992f2021-12-04T04:35:30ZDoes electrical stimulation improve healing in acute minor burn injury, as measured by bioimpedance spectroscopy? A single center, randomized, controlled trial2468-912210.1016/j.burnso.2021.11.001https://doaj.org/article/6dfc63275b8c4400b0f097b30536992f2022-01-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2468912221001127https://doaj.org/toc/2468-9122Background: Electrical stimulation (ES) has been shown to improve wound healing in chronic wounds. Recent studies in burn injured populations have demonstrated that ES improved edema and healing using short duration stimulation. This study utilized a low energy long duration ES using a portable device. The aim was to determine how this mode of stimulation influences the acute burn wound, as measured using bioimpedance spectroscopy (BIS). Our group has previously validated the use of BIS for measuring edema changes with wound healing in burn injured patients. Methods: This study is a within patient control, randomized study of 30 patients (24 male) presenting with burns to multiple limbs. One affected limb was randomized to receive ES and routine dressings. The other wound received routine care only. Minor burn wounds were stimulated for 10–14 days for more than 20 h/day. Serial localized BIS resistance and phase angle raw data measures were used to monitor edema and wound responses with treatment. Results: Multi-level mixed effects regression analyses demonstrated phase angle at 50 kHz increased at a faster rate in the stimulated wound. Stimulated wounds exhibited an increased rate of edema reduction as measured by extracellular tissue impedance. Conclusion: ES was confirmed to be an easily applied adjunct therapy to improve the rate of edema reduction in acute minor burn injury, and positively influences phase angle measures in the acute burn wound.Dale O. EdwickDana A. HinceJeremy M. RawlinsFiona M. WoodDale W. EdgarElsevierarticleWound healingBioelectrical impedanceElectrical stimulationBurnsEdemaDermatologyRL1-803Medical emergencies. Critical care. Intensive care. First aidRC86-88.9ENBurns Open, Vol 6, Iss 1, Pp 42-50 (2022)
institution	DOAJ
collection	DOAJ
language	EN
topic	Wound healing Bioelectrical impedance Electrical stimulation Burns Edema Dermatology RL1-803 Medical emergencies. Critical care. Intensive care. First aid RC86-88.9
spellingShingle	Wound healing Bioelectrical impedance Electrical stimulation Burns Edema Dermatology RL1-803 Medical emergencies. Critical care. Intensive care. First aid RC86-88.9 Dale O. Edwick Dana A. Hince Jeremy M. Rawlins Fiona M. Wood Dale W. Edgar Does electrical stimulation improve healing in acute minor burn injury, as measured by bioimpedance spectroscopy? A single center, randomized, controlled trial
description	Background: Electrical stimulation (ES) has been shown to improve wound healing in chronic wounds. Recent studies in burn injured populations have demonstrated that ES improved edema and healing using short duration stimulation. This study utilized a low energy long duration ES using a portable device. The aim was to determine how this mode of stimulation influences the acute burn wound, as measured using bioimpedance spectroscopy (BIS). Our group has previously validated the use of BIS for measuring edema changes with wound healing in burn injured patients. Methods: This study is a within patient control, randomized study of 30 patients (24 male) presenting with burns to multiple limbs. One affected limb was randomized to receive ES and routine dressings. The other wound received routine care only. Minor burn wounds were stimulated for 10–14 days for more than 20 h/day. Serial localized BIS resistance and phase angle raw data measures were used to monitor edema and wound responses with treatment. Results: Multi-level mixed effects regression analyses demonstrated phase angle at 50 kHz increased at a faster rate in the stimulated wound. Stimulated wounds exhibited an increased rate of edema reduction as measured by extracellular tissue impedance. Conclusion: ES was confirmed to be an easily applied adjunct therapy to improve the rate of edema reduction in acute minor burn injury, and positively influences phase angle measures in the acute burn wound.
format	article
author	Dale O. Edwick Dana A. Hince Jeremy M. Rawlins Fiona M. Wood Dale W. Edgar
author_facet	Dale O. Edwick Dana A. Hince Jeremy M. Rawlins Fiona M. Wood Dale W. Edgar
author_sort	Dale O. Edwick
title	Does electrical stimulation improve healing in acute minor burn injury, as measured by bioimpedance spectroscopy? A single center, randomized, controlled trial
title_short	Does electrical stimulation improve healing in acute minor burn injury, as measured by bioimpedance spectroscopy? A single center, randomized, controlled trial
title_full	Does electrical stimulation improve healing in acute minor burn injury, as measured by bioimpedance spectroscopy? A single center, randomized, controlled trial
title_fullStr	Does electrical stimulation improve healing in acute minor burn injury, as measured by bioimpedance spectroscopy? A single center, randomized, controlled trial
title_full_unstemmed	Does electrical stimulation improve healing in acute minor burn injury, as measured by bioimpedance spectroscopy? A single center, randomized, controlled trial
title_sort	does electrical stimulation improve healing in acute minor burn injury, as measured by bioimpedance spectroscopy? a single center, randomized, controlled trial
publisher	Elsevier
publishDate	2022
url	https://doaj.org/article/6dfc63275b8c4400b0f097b30536992f
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Does electrical stimulation improve healing in acute minor burn injury, as measured by bioimpedance spectroscopy? A single center, randomized, controlled trial

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