Kidney cytosine methylation changes improve renal function decline estimation in patients with diabetic kidney disease

Kidney cytosine methylation changes improve renal function decline estimation in patients with diabetic kidney disease

Patients with diabetes commonly develop diabetic kidney disease (DKD). Here Gluck et al. identify a set of probes differentially methylated in renal samples from patients with DKD, and find that inclusion of these methylation probes improves current prediction models of renal function decline.

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Detalles Bibliográficos
Autores principales: Caroline Gluck, Chengxiang Qiu, Sang Youb Han, Matthew Palmer, Jihwan Park, Yi-An Ko, Yuting Guan, Xin Sheng, Robert L. Hanson, Jing Huang, Yong Chen, Ae Seo Deok Park, Maria Concepcion Izquierdo, Ioannis Mantzaris, Amit Verma, James Pullman, Hongzhe Li, Katalin Susztak
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Science
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Acceso en línea:https://doaj.org/article/6e0ad1e89bd141cab012936df003ecb2
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Descripción
Sumario:Patients with diabetes commonly develop diabetic kidney disease (DKD). Here Gluck et al. identify a set of probes differentially methylated in renal samples from patients with DKD, and find that inclusion of these methylation probes improves current prediction models of renal function decline.

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