Kidney cytosine methylation changes improve renal function decline estimation in patients with diabetic kidney disease

Patients with diabetes commonly develop diabetic kidney disease (DKD). Here Gluck et al. identify a set of probes differentially methylated in renal samples from patients with DKD, and find that inclusion of these methylation probes improves current prediction models of renal function decline.

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Autores principales: Caroline Gluck, Chengxiang Qiu, Sang Youb Han, Matthew Palmer, Jihwan Park, Yi-An Ko, Yuting Guan, Xin Sheng, Robert L. Hanson, Jing Huang, Yong Chen, Ae Seo Deok Park, Maria Concepcion Izquierdo, Ioannis Mantzaris, Amit Verma, James Pullman, Hongzhe Li, Katalin Susztak
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/6e0ad1e89bd141cab012936df003ecb2
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spelling oai:doaj.org-article:6e0ad1e89bd141cab012936df003ecb22021-12-02T16:58:07ZKidney cytosine methylation changes improve renal function decline estimation in patients with diabetic kidney disease10.1038/s41467-019-10378-82041-1723https://doaj.org/article/6e0ad1e89bd141cab012936df003ecb22019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10378-8https://doaj.org/toc/2041-1723Patients with diabetes commonly develop diabetic kidney disease (DKD). Here Gluck et al. identify a set of probes differentially methylated in renal samples from patients with DKD, and find that inclusion of these methylation probes improves current prediction models of renal function decline.Caroline GluckChengxiang QiuSang Youb HanMatthew PalmerJihwan ParkYi-An KoYuting GuanXin ShengRobert L. HansonJing HuangYong ChenAe Seo Deok ParkMaria Concepcion IzquierdoIoannis MantzarisAmit VermaJames PullmanHongzhe LiKatalin SusztakNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Caroline Gluck
Chengxiang Qiu
Sang Youb Han
Matthew Palmer
Jihwan Park
Yi-An Ko
Yuting Guan
Xin Sheng
Robert L. Hanson
Jing Huang
Yong Chen
Ae Seo Deok Park
Maria Concepcion Izquierdo
Ioannis Mantzaris
Amit Verma
James Pullman
Hongzhe Li
Katalin Susztak
Kidney cytosine methylation changes improve renal function decline estimation in patients with diabetic kidney disease
description Patients with diabetes commonly develop diabetic kidney disease (DKD). Here Gluck et al. identify a set of probes differentially methylated in renal samples from patients with DKD, and find that inclusion of these methylation probes improves current prediction models of renal function decline.
format article
author Caroline Gluck
Chengxiang Qiu
Sang Youb Han
Matthew Palmer
Jihwan Park
Yi-An Ko
Yuting Guan
Xin Sheng
Robert L. Hanson
Jing Huang
Yong Chen
Ae Seo Deok Park
Maria Concepcion Izquierdo
Ioannis Mantzaris
Amit Verma
James Pullman
Hongzhe Li
Katalin Susztak
author_facet Caroline Gluck
Chengxiang Qiu
Sang Youb Han
Matthew Palmer
Jihwan Park
Yi-An Ko
Yuting Guan
Xin Sheng
Robert L. Hanson
Jing Huang
Yong Chen
Ae Seo Deok Park
Maria Concepcion Izquierdo
Ioannis Mantzaris
Amit Verma
James Pullman
Hongzhe Li
Katalin Susztak
author_sort Caroline Gluck
title Kidney cytosine methylation changes improve renal function decline estimation in patients with diabetic kidney disease
title_short Kidney cytosine methylation changes improve renal function decline estimation in patients with diabetic kidney disease
title_full Kidney cytosine methylation changes improve renal function decline estimation in patients with diabetic kidney disease
title_fullStr Kidney cytosine methylation changes improve renal function decline estimation in patients with diabetic kidney disease
title_full_unstemmed Kidney cytosine methylation changes improve renal function decline estimation in patients with diabetic kidney disease
title_sort kidney cytosine methylation changes improve renal function decline estimation in patients with diabetic kidney disease
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/6e0ad1e89bd141cab012936df003ecb2
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