mRNA display with library of even-distribution reveals cellular interactors of influenza virus NS1
Identification of low abundance proteins interacting with viral proteins can be challenging. Here, Du et al. develop an mRNA display approach with a library of even distribution, identify host proteins interacting with NS1 protein of influenza A virus, and show that one interactor provides a means t...
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Nature Portfolio
2020
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oai:doaj.org-article:6e0ba4fb71cb4e7ea04eed81d78d3f6a2021-12-02T16:50:30ZmRNA display with library of even-distribution reveals cellular interactors of influenza virus NS110.1038/s41467-020-16140-92041-1723https://doaj.org/article/6e0ba4fb71cb4e7ea04eed81d78d3f6a2020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16140-9https://doaj.org/toc/2041-1723Identification of low abundance proteins interacting with viral proteins can be challenging. Here, Du et al. develop an mRNA display approach with a library of even distribution, identify host proteins interacting with NS1 protein of influenza A virus, and show that one interactor provides a means to regulate cellular fatty acids synthesis.Yushen DuJudd F. HultquistQuan ZhouAnders OlsonYenwen TsengTian-hao ZhangMengying HongKejun TangLiubo ChenXiangzhi MengMichael J. McGregorLei DaiDanyang GongLaura Martin-SanchoSumit ChandaXinming LiSteve BensengerNevan J. KroganRen SunNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Yushen Du Judd F. Hultquist Quan Zhou Anders Olson Yenwen Tseng Tian-hao Zhang Mengying Hong Kejun Tang Liubo Chen Xiangzhi Meng Michael J. McGregor Lei Dai Danyang Gong Laura Martin-Sancho Sumit Chanda Xinming Li Steve Bensenger Nevan J. Krogan Ren Sun mRNA display with library of even-distribution reveals cellular interactors of influenza virus NS1 |
| description |
Identification of low abundance proteins interacting with viral proteins can be challenging. Here, Du et al. develop an mRNA display approach with a library of even distribution, identify host proteins interacting with NS1 protein of influenza A virus, and show that one interactor provides a means to regulate cellular fatty acids synthesis. |
| format |
article |
| author |
Yushen Du Judd F. Hultquist Quan Zhou Anders Olson Yenwen Tseng Tian-hao Zhang Mengying Hong Kejun Tang Liubo Chen Xiangzhi Meng Michael J. McGregor Lei Dai Danyang Gong Laura Martin-Sancho Sumit Chanda Xinming Li Steve Bensenger Nevan J. Krogan Ren Sun |
| author_facet |
Yushen Du Judd F. Hultquist Quan Zhou Anders Olson Yenwen Tseng Tian-hao Zhang Mengying Hong Kejun Tang Liubo Chen Xiangzhi Meng Michael J. McGregor Lei Dai Danyang Gong Laura Martin-Sancho Sumit Chanda Xinming Li Steve Bensenger Nevan J. Krogan Ren Sun |
| author_sort |
Yushen Du |
| title |
mRNA display with library of even-distribution reveals cellular interactors of influenza virus NS1 |
| title_short |
mRNA display with library of even-distribution reveals cellular interactors of influenza virus NS1 |
| title_full |
mRNA display with library of even-distribution reveals cellular interactors of influenza virus NS1 |
| title_fullStr |
mRNA display with library of even-distribution reveals cellular interactors of influenza virus NS1 |
| title_full_unstemmed |
mRNA display with library of even-distribution reveals cellular interactors of influenza virus NS1 |
| title_sort |
mrna display with library of even-distribution reveals cellular interactors of influenza virus ns1 |
| publisher |
Nature Portfolio |
| publishDate |
2020 |
| url |
https://doaj.org/article/6e0ba4fb71cb4e7ea04eed81d78d3f6a |
| work_keys_str_mv |
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