INFLUENCE OF THIMALIN UPON IMMUNITY AND LYMPHOCYTE-PLATELET ADHESION IN CHILDREN WITH SECONDARY INFECTIOUS ENDOCARDITIS
In the children with secondary infective endocarditis, the contents of TNK cells was found to be decreased. Same patients exhibit low concentrations of total IgG and its subclasses, IgG1 and IgG2 subclasses decreased, whereas IgG4 levels are increased. Stimulated phagocytic response is also decrease...
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oai:doaj.org-article:6e0d1508be424c15966f06574f0618182021-11-18T08:03:38ZINFLUENCE OF THIMALIN UPON IMMUNITY AND LYMPHOCYTE-PLATELET ADHESION IN CHILDREN WITH SECONDARY INFECTIOUS ENDOCARDITIS1563-06252313-741X10.15789/1563-0625-2010-4-5-381-386https://doaj.org/article/6e0d1508be424c15966f06574f0618182014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/207https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XIn the children with secondary infective endocarditis, the contents of TNK cells was found to be decreased. Same patients exhibit low concentrations of total IgG and its subclasses, IgG1 and IgG2 subclasses decreased, whereas IgG4 levels are increased. Stimulated phagocytic response is also decreased in these patients, along with increased numbers of lymphocyte/platelet cell aggregates. Effect of a conventional treatment with addition of thymalin when treating secondary infective endocarditis, was more pronounced, in comparison with conventional therapy, with respect to restoration of humoral immunity, phagocytic activity of leukocytes and lymphocyte-platelet adhesion.A. B. DolinaB. I. KuznikV. J RosenbergT. M. VishnyakovaYu. A. VitkovskySPb RAACIarticleinfectious endocarditisthymalinimmunityphagocytosislymphocyte/platelet aggregationsImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 12, Iss 4-5, Pp 381-386 (2014) |
institution |
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DOAJ |
language |
RU |
topic |
infectious endocarditis thymalin immunity phagocytosis lymphocyte/platelet aggregations Immunologic diseases. Allergy RC581-607 |
spellingShingle |
infectious endocarditis thymalin immunity phagocytosis lymphocyte/platelet aggregations Immunologic diseases. Allergy RC581-607 A. B. Dolina B. I. Kuznik V. J Rosenberg T. M. Vishnyakova Yu. A. Vitkovsky INFLUENCE OF THIMALIN UPON IMMUNITY AND LYMPHOCYTE-PLATELET ADHESION IN CHILDREN WITH SECONDARY INFECTIOUS ENDOCARDITIS |
description |
In the children with secondary infective endocarditis, the contents of TNK cells was found to be decreased. Same patients exhibit low concentrations of total IgG and its subclasses, IgG1 and IgG2 subclasses decreased, whereas IgG4 levels are increased. Stimulated phagocytic response is also decreased in these patients, along with increased numbers of lymphocyte/platelet cell aggregates. Effect of a conventional treatment with addition of thymalin when treating secondary infective endocarditis, was more pronounced, in comparison with conventional therapy, with respect to restoration of humoral immunity, phagocytic activity of leukocytes and lymphocyte-platelet adhesion. |
format |
article |
author |
A. B. Dolina B. I. Kuznik V. J Rosenberg T. M. Vishnyakova Yu. A. Vitkovsky |
author_facet |
A. B. Dolina B. I. Kuznik V. J Rosenberg T. M. Vishnyakova Yu. A. Vitkovsky |
author_sort |
A. B. Dolina |
title |
INFLUENCE OF THIMALIN UPON IMMUNITY AND LYMPHOCYTE-PLATELET ADHESION IN CHILDREN WITH SECONDARY INFECTIOUS ENDOCARDITIS |
title_short |
INFLUENCE OF THIMALIN UPON IMMUNITY AND LYMPHOCYTE-PLATELET ADHESION IN CHILDREN WITH SECONDARY INFECTIOUS ENDOCARDITIS |
title_full |
INFLUENCE OF THIMALIN UPON IMMUNITY AND LYMPHOCYTE-PLATELET ADHESION IN CHILDREN WITH SECONDARY INFECTIOUS ENDOCARDITIS |
title_fullStr |
INFLUENCE OF THIMALIN UPON IMMUNITY AND LYMPHOCYTE-PLATELET ADHESION IN CHILDREN WITH SECONDARY INFECTIOUS ENDOCARDITIS |
title_full_unstemmed |
INFLUENCE OF THIMALIN UPON IMMUNITY AND LYMPHOCYTE-PLATELET ADHESION IN CHILDREN WITH SECONDARY INFECTIOUS ENDOCARDITIS |
title_sort |
influence of thimalin upon immunity and lymphocyte-platelet adhesion in children with secondary infectious endocarditis |
publisher |
SPb RAACI |
publishDate |
2014 |
url |
https://doaj.org/article/6e0d1508be424c15966f06574f061818 |
work_keys_str_mv |
AT abdolina influenceofthimalinuponimmunityandlymphocyteplateletadhesioninchildrenwithsecondaryinfectiousendocarditis AT bikuznik influenceofthimalinuponimmunityandlymphocyteplateletadhesioninchildrenwithsecondaryinfectiousendocarditis AT vjrosenberg influenceofthimalinuponimmunityandlymphocyteplateletadhesioninchildrenwithsecondaryinfectiousendocarditis AT tmvishnyakova influenceofthimalinuponimmunityandlymphocyteplateletadhesioninchildrenwithsecondaryinfectiousendocarditis AT yuavitkovsky influenceofthimalinuponimmunityandlymphocyteplateletadhesioninchildrenwithsecondaryinfectiousendocarditis |
_version_ |
1718422550579511296 |