INFLUENCE OF THIMALIN UPON IMMUNITY AND LYMPHOCYTE-PLATELET ADHESION IN CHILDREN WITH SECONDARY INFECTIOUS ENDOCARDITIS

In the children with secondary infective endocarditis, the contents of TNK cells was found to be decreased. Same patients exhibit low concentrations of total IgG and its subclasses, IgG1 and IgG2 subclasses decreased, whereas IgG4 levels are increased. Stimulated phagocytic response is also decrease...

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Autores principales: A. B. Dolina, B. I. Kuznik, V. J Rosenberg, T. M. Vishnyakova, Yu. A. Vitkovsky
Formato: article
Lenguaje:RU
Publicado: SPb RAACI 2014
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Acceso en línea:https://doaj.org/article/6e0d1508be424c15966f06574f061818
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spelling oai:doaj.org-article:6e0d1508be424c15966f06574f0618182021-11-18T08:03:38ZINFLUENCE OF THIMALIN UPON IMMUNITY AND LYMPHOCYTE-PLATELET ADHESION IN CHILDREN WITH SECONDARY INFECTIOUS ENDOCARDITIS1563-06252313-741X10.15789/1563-0625-2010-4-5-381-386https://doaj.org/article/6e0d1508be424c15966f06574f0618182014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/207https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XIn the children with secondary infective endocarditis, the contents of TNK cells was found to be decreased. Same patients exhibit low concentrations of total IgG and its subclasses, IgG1 and IgG2 subclasses decreased, whereas IgG4 levels are increased. Stimulated phagocytic response is also decreased in these patients, along with increased numbers of lymphocyte/platelet cell aggregates. Effect of a conventional treatment with addition of thymalin when treating secondary infective endocarditis, was more pronounced, in comparison with conventional therapy, with respect to restoration of humoral immunity, phagocytic activity of leukocytes and lymphocyte-platelet adhesion.A. B. DolinaB. I. KuznikV. J RosenbergT. M. VishnyakovaYu. A. VitkovskySPb RAACIarticleinfectious endocarditisthymalinimmunityphagocytosislymphocyte/platelet aggregationsImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 12, Iss 4-5, Pp 381-386 (2014)
institution DOAJ
collection DOAJ
language RU
topic infectious endocarditis
thymalin
immunity
phagocytosis
lymphocyte/platelet aggregations
Immunologic diseases. Allergy
RC581-607
spellingShingle infectious endocarditis
thymalin
immunity
phagocytosis
lymphocyte/platelet aggregations
Immunologic diseases. Allergy
RC581-607
A. B. Dolina
B. I. Kuznik
V. J Rosenberg
T. M. Vishnyakova
Yu. A. Vitkovsky
INFLUENCE OF THIMALIN UPON IMMUNITY AND LYMPHOCYTE-PLATELET ADHESION IN CHILDREN WITH SECONDARY INFECTIOUS ENDOCARDITIS
description In the children with secondary infective endocarditis, the contents of TNK cells was found to be decreased. Same patients exhibit low concentrations of total IgG and its subclasses, IgG1 and IgG2 subclasses decreased, whereas IgG4 levels are increased. Stimulated phagocytic response is also decreased in these patients, along with increased numbers of lymphocyte/platelet cell aggregates. Effect of a conventional treatment with addition of thymalin when treating secondary infective endocarditis, was more pronounced, in comparison with conventional therapy, with respect to restoration of humoral immunity, phagocytic activity of leukocytes and lymphocyte-platelet adhesion.
format article
author A. B. Dolina
B. I. Kuznik
V. J Rosenberg
T. M. Vishnyakova
Yu. A. Vitkovsky
author_facet A. B. Dolina
B. I. Kuznik
V. J Rosenberg
T. M. Vishnyakova
Yu. A. Vitkovsky
author_sort A. B. Dolina
title INFLUENCE OF THIMALIN UPON IMMUNITY AND LYMPHOCYTE-PLATELET ADHESION IN CHILDREN WITH SECONDARY INFECTIOUS ENDOCARDITIS
title_short INFLUENCE OF THIMALIN UPON IMMUNITY AND LYMPHOCYTE-PLATELET ADHESION IN CHILDREN WITH SECONDARY INFECTIOUS ENDOCARDITIS
title_full INFLUENCE OF THIMALIN UPON IMMUNITY AND LYMPHOCYTE-PLATELET ADHESION IN CHILDREN WITH SECONDARY INFECTIOUS ENDOCARDITIS
title_fullStr INFLUENCE OF THIMALIN UPON IMMUNITY AND LYMPHOCYTE-PLATELET ADHESION IN CHILDREN WITH SECONDARY INFECTIOUS ENDOCARDITIS
title_full_unstemmed INFLUENCE OF THIMALIN UPON IMMUNITY AND LYMPHOCYTE-PLATELET ADHESION IN CHILDREN WITH SECONDARY INFECTIOUS ENDOCARDITIS
title_sort influence of thimalin upon immunity and lymphocyte-platelet adhesion in children with secondary infectious endocarditis
publisher SPb RAACI
publishDate 2014
url https://doaj.org/article/6e0d1508be424c15966f06574f061818
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