Post-translational modifications modulate ligand recognition by the third PDZ domain of the MAGUK protein PSD-95.
The relative promiscuity of hub proteins such as postsynaptic density protein-95 (PSD-95) can be achieved by alternative splicing, allosteric regulation, and post-translational modifications, the latter of which is the most efficient method of accelerating cellular responses to environmental changes...
Guardado en:
Autores principales: | Javier Murciano-Calles, Carles Corbi-Verge, Adela M Candel, Irene Luque, Jose C Martinez |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2014
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Materias: | |
Acceso en línea: | https://doaj.org/article/6e1b528ce45546eb8b51715f834eb22b |
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