The self-interaction of a nodavirus replicase is enhanced by mitochondrial membrane lipids.

The self-interaction of a nodavirus replicase is enhanced by mitochondrial membrane lipids.

RNA replication of positive-strand (+)RNA viruses requires the protein-protein interactions among viral replicases and the association of viral replicases with intracellular membranes. Protein A from Wuhan nodavirus (WhNV), which closely associate with mitochondrial membranes, is the sole replicase...

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Autores principales: Yang Qiu, Zhaowei Wang, Yongxiang Liu, Yajuan Han, Meng Miao, Nan Qi, Jie Yang, Hongjie Xia, Xiaofeng Li, Cheng-Feng Qin, Yuanyang Hu, Xi Zhou
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/6e1ee54e0c5c45ef823173106c5f2041
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