CircRNA circ-NNT mediates myocardial ischemia/reperfusion injury through activating pyroptosis by sponging miR-33a-5p and regulating USP46 expression

Abstract Pyroptosis has been implicated in the pathophysiology of myocardial infarction (MI) in rodents, but its contribution to reperfusion injury in MI patients is unclear. Here, we evaluated pyroptosis in MI patients in vitro and in vivo models of myocardial ischemia/reperfusion (I/R) injury. We...

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Autores principales: Xiaomiao Ye, Yanwen Hang, Yi Lu, Dandan Li, Fangfang Shen, Ping Guan, Jian Dong, Ludong Shi, Wei Hu
Formato: article
Lenguaje:EN
Publicado: Nature Publishing Group 2021
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Acceso en línea:https://doaj.org/article/6e22a074b41846aa96124c03e64ac87a
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