Effect of trabeculectomy on retrobulbar circulation and visual field progression in patients with primary open-angle glaucoma

Yoshio Yamazaki, Fukuko HayamizuDepartment of Ophthalmology, Division of Visual Science, Nihon University School of Medicine, Tokyo, JapanBackground: The purpose of this study was to investigate the relationship between retrobulbar circulation and visual field change in eyes with primary open-angle...

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Autores principales:	Yamazaki Y, Hayamizu F
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2012
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/6e279021be244bbcb8a114ac1e92c823
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spelling	oai:doaj.org-article:6e279021be244bbcb8a114ac1e92c8232021-12-02T01:48:52ZEffect of trabeculectomy on retrobulbar circulation and visual field progression in patients with primary open-angle glaucoma1177-54671177-5483https://doaj.org/article/6e279021be244bbcb8a114ac1e92c8232012-09-01T00:00:00Zhttp://www.dovepress.com/effect-of-trabeculectomy-on-retrobulbar-circulation-and-visual-field-p-a11069https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Yoshio Yamazaki, Fukuko HayamizuDepartment of Ophthalmology, Division of Visual Science, Nihon University School of Medicine, Tokyo, JapanBackground: The purpose of this study was to investigate the relationship between retrobulbar circulation and visual field change in eyes with primary open-angle glaucoma following unilateral trabeculectomy.Methods: Twenty-one patients with primary open-angle glaucoma were prospectively enrolled. Retrobulbar circulation was evaluated using color Doppler imaging. The peak systolic velocity, end-diastolic velocity, and resistive index were evaluated in the central retinal artery, temporal site of the short posterior ciliary artery (t-SPCA), and nasal site of the short posterior ciliary artery (n-SPCA). Visual field examinations were performed using a Humphrey visual field analyzer before surgery and trimonthly for 12 months postoperatively.Results: In the operative eyes, the end-diastolic velocity was significantly increased in the central retinal artery (P = 0.005, analysis of variance), t-SPCA (P = 0.005), and n-SPCA (P = 0.027). The resistive index was significantly decreased in the central retinal artery (P = 0.003), t-SPCA (P = 0.000), and n-SPCA (P = 0.010) postoperatively compared with preoperatively. The nonoperative contralateral eyes did not show a significant change in end-diastolic velocity or resistive index for either the SPCA or central retinal artery. The mean deviation slope in the operative eyes (-0.26 &plusmn; 0.64 dB/year) was significantly slower than that in the nonoperative eyes (-0.65 &plusmn; 0.70 dB/year; P = 0.047, Mann-Whitney U test).Conclusion: These results suggest that trabeculectomy improves the retrobulbar circulation and prevents the progression of visual field changes in patients with primary open-angle glaucoma.Keywords: trabeculectomy, retrobulbar circulation, visual field, color Doppler imagingYamazaki YHayamizu FDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2012, Iss default, Pp 1539-1545 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Yamazaki Y Hayamizu F Effect of trabeculectomy on retrobulbar circulation and visual field progression in patients with primary open-angle glaucoma
description	Yoshio Yamazaki, Fukuko HayamizuDepartment of Ophthalmology, Division of Visual Science, Nihon University School of Medicine, Tokyo, JapanBackground: The purpose of this study was to investigate the relationship between retrobulbar circulation and visual field change in eyes with primary open-angle glaucoma following unilateral trabeculectomy.Methods: Twenty-one patients with primary open-angle glaucoma were prospectively enrolled. Retrobulbar circulation was evaluated using color Doppler imaging. The peak systolic velocity, end-diastolic velocity, and resistive index were evaluated in the central retinal artery, temporal site of the short posterior ciliary artery (t-SPCA), and nasal site of the short posterior ciliary artery (n-SPCA). Visual field examinations were performed using a Humphrey visual field analyzer before surgery and trimonthly for 12 months postoperatively.Results: In the operative eyes, the end-diastolic velocity was significantly increased in the central retinal artery (P = 0.005, analysis of variance), t-SPCA (P = 0.005), and n-SPCA (P = 0.027). The resistive index was significantly decreased in the central retinal artery (P = 0.003), t-SPCA (P = 0.000), and n-SPCA (P = 0.010) postoperatively compared with preoperatively. The nonoperative contralateral eyes did not show a significant change in end-diastolic velocity or resistive index for either the SPCA or central retinal artery. The mean deviation slope in the operative eyes (-0.26 &plusmn; 0.64 dB/year) was significantly slower than that in the nonoperative eyes (-0.65 &plusmn; 0.70 dB/year; P = 0.047, Mann-Whitney U test).Conclusion: These results suggest that trabeculectomy improves the retrobulbar circulation and prevents the progression of visual field changes in patients with primary open-angle glaucoma.Keywords: trabeculectomy, retrobulbar circulation, visual field, color Doppler imaging
format	article
author	Yamazaki Y Hayamizu F
author_facet	Yamazaki Y Hayamizu F
author_sort	Yamazaki Y
title	Effect of trabeculectomy on retrobulbar circulation and visual field progression in patients with primary open-angle glaucoma
title_short	Effect of trabeculectomy on retrobulbar circulation and visual field progression in patients with primary open-angle glaucoma
title_full	Effect of trabeculectomy on retrobulbar circulation and visual field progression in patients with primary open-angle glaucoma
title_fullStr	Effect of trabeculectomy on retrobulbar circulation and visual field progression in patients with primary open-angle glaucoma
title_full_unstemmed	Effect of trabeculectomy on retrobulbar circulation and visual field progression in patients with primary open-angle glaucoma
title_sort	effect of trabeculectomy on retrobulbar circulation and visual field progression in patients with primary open-angle glaucoma
publisher	Dove Medical Press
publishDate	2012
url	https://doaj.org/article/6e279021be244bbcb8a114ac1e92c823
work_keys_str_mv	AT yamazakiy effectoftrabeculectomyonretrobulbarcirculationandvisualfieldprogressioninpatientswithprimaryopenangleglaucoma AT hayamizuf effectoftrabeculectomyonretrobulbarcirculationandvisualfieldprogressioninpatientswithprimaryopenangleglaucoma
_version_	1718402900781170688

Effect of trabeculectomy on retrobulbar circulation and visual field progression in patients with primary open-angle glaucoma

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