Development and validation of a timely and representative finite element human spine model for biomechanical simulations

Abstract Numerous spine Finite Element (FE) models have been developed to assess spinal tolerances, spinal loadings and low back pain-related issues. However, justified simplifications, in terms of tissue decomposition and inclusion, for such a complex system may overlook crucial information. Thus,...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Ibrahim El Bojairami, Khaled El-Monajjed, Mark Driscoll
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/6e30b580eeda4799b8ca54cf21a16226
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:6e30b580eeda4799b8ca54cf21a16226
record_format	dspace
spelling	oai:doaj.org-article:6e30b580eeda4799b8ca54cf21a162262021-12-02T16:18:03ZDevelopment and validation of a timely and representative finite element human spine model for biomechanical simulations10.1038/s41598-020-77469-12045-2322https://doaj.org/article/6e30b580eeda4799b8ca54cf21a162262020-12-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-77469-1https://doaj.org/toc/2045-2322Abstract Numerous spine Finite Element (FE) models have been developed to assess spinal tolerances, spinal loadings and low back pain-related issues. However, justified simplifications, in terms of tissue decomposition and inclusion, for such a complex system may overlook crucial information. Thus, the purpose of this research was to develop and validate a comprehensive and representative spine FE model inclusive of an accurate representation of all major torso elements. A comprehensive model comprised of 273 tissues was developed via a novel FE meshing method to enhance computational feasibility. A comprehensive set of indirect validation tests were carried out to validate every aspect of the model. Under an increasing angular displacement of 24°–41°, the lumbar spine recorded an increasing moment from 5.5 to 9.3 Nm with an increase in IVD pressures from 0.41 to 0.66 MPa. Under forward flexion, vertical vertebral displacements simulated a 6% and 13% maximum discrepancy for intra-abdominal and intramuscular pressure results, all closely resembling previously documented in silico measured values. The developed state-of-the-art model includes most physiological tissues known to contribute to spinal loadings. Given the simulation’s accuracy, confirmed by its validation tests, the developed model may serve as a reliable spinal assessment tool.Ibrahim El BojairamiKhaled El-MonajjedMark DriscollNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Ibrahim El Bojairami Khaled El-Monajjed Mark Driscoll Development and validation of a timely and representative finite element human spine model for biomechanical simulations
description	Abstract Numerous spine Finite Element (FE) models have been developed to assess spinal tolerances, spinal loadings and low back pain-related issues. However, justified simplifications, in terms of tissue decomposition and inclusion, for such a complex system may overlook crucial information. Thus, the purpose of this research was to develop and validate a comprehensive and representative spine FE model inclusive of an accurate representation of all major torso elements. A comprehensive model comprised of 273 tissues was developed via a novel FE meshing method to enhance computational feasibility. A comprehensive set of indirect validation tests were carried out to validate every aspect of the model. Under an increasing angular displacement of 24°–41°, the lumbar spine recorded an increasing moment from 5.5 to 9.3 Nm with an increase in IVD pressures from 0.41 to 0.66 MPa. Under forward flexion, vertical vertebral displacements simulated a 6% and 13% maximum discrepancy for intra-abdominal and intramuscular pressure results, all closely resembling previously documented in silico measured values. The developed state-of-the-art model includes most physiological tissues known to contribute to spinal loadings. Given the simulation’s accuracy, confirmed by its validation tests, the developed model may serve as a reliable spinal assessment tool.
format	article
author	Ibrahim El Bojairami Khaled El-Monajjed Mark Driscoll
author_facet	Ibrahim El Bojairami Khaled El-Monajjed Mark Driscoll
author_sort	Ibrahim El Bojairami
title	Development and validation of a timely and representative finite element human spine model for biomechanical simulations
title_short	Development and validation of a timely and representative finite element human spine model for biomechanical simulations
title_full	Development and validation of a timely and representative finite element human spine model for biomechanical simulations
title_fullStr	Development and validation of a timely and representative finite element human spine model for biomechanical simulations
title_full_unstemmed	Development and validation of a timely and representative finite element human spine model for biomechanical simulations
title_sort	development and validation of a timely and representative finite element human spine model for biomechanical simulations
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/6e30b580eeda4799b8ca54cf21a16226
work_keys_str_mv	AT ibrahimelbojairami developmentandvalidationofatimelyandrepresentativefiniteelementhumanspinemodelforbiomechanicalsimulations AT khaledelmonajjed developmentandvalidationofatimelyandrepresentativefiniteelementhumanspinemodelforbiomechanicalsimulations AT markdriscoll developmentandvalidationofatimelyandrepresentativefiniteelementhumanspinemodelforbiomechanicalsimulations
_version_	1718384236121030656

Development and validation of a timely and representative finite element human spine model for biomechanical simulations

Ejemplares similares