Clonal architectures predict clinical outcome in clear cell renal cell carcinoma

Clear cell renal cell carcinoma (ccRCC) is a urogenital cancer with a well-defined genetic landscape. Here, the authors analyse the clonal architecture of ccRCC patients from three populations, and find prognostic subtypes linked to immune infiltrates and clonal architecture.

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Auteurs principaux: Yi Huang, Jiayin Wang, Peilin Jia, Xiangchun Li, Guangsheng Pei, Changxi Wang, Xiaodong Fang, Zhongming Zhao, Zhiming Cai, Xin Yi, Song Wu, Baifeng Zhang
Format: article
Langue:EN
Publié: Nature Portfolio 2019
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Accès en ligne:https://doaj.org/article/6e325ecbfb32442eb1a9e808c83d9a19
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Résumé:Clear cell renal cell carcinoma (ccRCC) is a urogenital cancer with a well-defined genetic landscape. Here, the authors analyse the clonal architecture of ccRCC patients from three populations, and find prognostic subtypes linked to immune infiltrates and clonal architecture.